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Page 1
Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.
d'Orange M, Aurégan G, Cheramy D, Gaudin-Guérif M, Lieger S, Guillermier M, Stimmer L, Joséphine C, Hérard AS, Gaillard MC, Petit F, Kiessling MC, Schmitz C, Colin M, Buée L, Panayi F, Diguet E, Brouillet E, Hantraye P, Bemelmans AP, Cambon K. d'Orange M, et al. Among authors: guillermier m. Brain. 2018 Feb 1;141(2):535-549. doi: 10.1093/brain/awx342. Brain. 2018. PMID: 29253129 Free PMC article.
The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: guillermier m. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K. Maté de Gérando A, et al. Among authors: guillermier m. Brain. 2021 May 7;144(4):1167-1182. doi: 10.1093/brain/awab011. Brain. 2021. PMID: 33842937
The C-terminal domain of LRRK2 with the G2019S mutation is sufficient to produce neurodegeneration of dopaminergic neurons in vivo.
Cresto N, Gaillard MC, Gardier C, Gubinelli F, Diguet E, Bellet D, Legroux L, Mitja J, Auregan G, Guillermier M, Josephine C, Jan C, Dufour N, Joliot A, Hantraye P, Bonvento G, Déglon N, Bemelmans AP, Cambon K, Liot G, Brouillet E. Cresto N, et al. Among authors: guillermier m. Neurobiol Dis. 2020 Feb;134:104614. doi: 10.1016/j.nbd.2019.104614. Epub 2019 Oct 9. Neurobiol Dis. 2020. PMID: 31605779 Free article.
Complex roles for reactive astrocytes in the triple transgenic mouse model of Alzheimer disease.
Guillemaud O, Ceyzériat K, Saint-Georges T, Cambon K, Petit F, Ben Haim L, Carrillo-de Sauvage MA, Guillermier M, Bernier S, Hérard AS, Joséphine C, Bémelmans AP, Brouillet E, Hantraye P, Bonvento G, Escartin C. Guillemaud O, et al. Among authors: guillermier m. Neurobiol Aging. 2020 Jun;90:135-146. doi: 10.1016/j.neurobiolaging.2020.02.010. Epub 2020 Feb 18. Neurobiol Aging. 2020. PMID: 32171592 Free article.
Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, Robil N, Kabani M, Melki R, De la Grange P, Bemelmans AP, Bonvento G, Deleuze JF, Hantraye P, Flament J, Bonnet E, Brohard S, Olaso R, Brouillet E, Carrillo-de Sauvage MA, Escartin C. Abjean L, et al. Among authors: guillermier m. Brain. 2023 Jan 5;146(1):149-166. doi: 10.1093/brain/awac068. Brain. 2023. PMID: 35298632
Capucin does not modify the toxicity of a mutant Huntingtin fragment in vivo.
Galvan L, Lepejová N, Gaillard MC, Malgorn C, Guillermier M, Houitte D, Bonvento G, Petit F, Dufour N, Héry P, Gérard M, Elalouf JM, Déglon N, Brouillet E, de Chaldée M. Galvan L, et al. Among authors: guillermier m. Neurobiol Aging. 2012 Aug;33(8):1845.e5-6. doi: 10.1016/j.neurobiolaging.2012.01.009. Epub 2012 Feb 24. Neurobiol Aging. 2012. PMID: 22365050
Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.
Francelle L, Galvan L, Gaillard MC, Guillermier M, Houitte D, Bonvento G, Petit F, Jan C, Dufour N, Hantraye P, Elalouf JM, De Chaldée M, Déglon N, Brouillet E. Francelle L, et al. Among authors: guillermier m. Hum Mol Genet. 2015 Mar 15;24(6):1563-73. doi: 10.1093/hmg/ddu571. Epub 2014 Nov 14. Hum Mol Genet. 2015. PMID: 25398949 Free PMC article.
Striatal long noncoding RNA Abhd11os is neuroprotective against an N-terminal fragment of mutant huntingtin in vivo.
Francelle L, Galvan L, Gaillard MC, Petit F, Bernay B, Guillermier M, Bonvento G, Dufour N, Elalouf JM, Hantraye P, Déglon N, de Chaldée M, Brouillet E. Francelle L, et al. Among authors: guillermier m. Neurobiol Aging. 2015 Mar;36(3):1601.e7-16. doi: 10.1016/j.neurobiolaging.2014.11.014. Epub 2014 Dec 18. Neurobiol Aging. 2015. PMID: 25619660 Free article.
The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo.
Cresto N, Gardier C, Gaillard MC, Gubinelli F, Roost P, Molina D, Josephine C, Dufour N, Auregan G, Guillermier M, Bernier S, Jan C, Gipchtein P, Hantraye P, Chartier-Harlin MC, Bonvento G, Van Camp N, Taymans JM, Cambon K, Liot G, Bemelmans AP, Brouillet E. Cresto N, et al. Among authors: guillermier m. Int J Mol Sci. 2021 Jun 23;22(13):6760. doi: 10.3390/ijms22136760. Int J Mol Sci. 2021. PMID: 34201785 Free PMC article.
41 results