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Single-cell RNA-sequencing of PBMCs from SAVI patients reveals disease-associated monocytes with elevated integrated stress response.
de Cevins C, Delage L, Batignes M, Riller Q, Luka M, Remaury A, Sorin B, Fali T, Masson C, Hoareau B, Meunier C, Parisot M, Zarhrate M, Pérot BP, García-Paredes V, Carbone F, Galliot L, Nal B, Pierre P, Canard L, Boussard C, Crickx E, Guillemot JC, Bader-Meunier B, Bélot A, Quartier P, Frémond ML, Neven B, Boldina G, Augé F, Alain F, Didier M, Rieux-Laucat F, Ménager MM. de Cevins C, et al. Among authors: guillemot jc. Cell Rep Med. 2023 Dec 19;4(12):101333. doi: 10.1016/j.xcrm.2023.101333. Cell Rep Med. 2023. PMID: 38118407 Free PMC article.
TEAD Inhibitors Sensitize KRASG12C Inhibitors via Dual Cell Cycle Arrest in KRASG12C-Mutant NSCLC.
Tammaccaro SL, Prigent P, Le Bail JC, Dos-Santos O, Dassencourt L, Eskandar M, Buzy A, Venier O, Guillemot JC, Veeranagouda Y, Didier M, Spanakis E, Kanno T, Cesaroni M, Mathieu S, Canard L, Casse A, Windenberger F, Calvet L, Noblet L, Sidhu S, Debussche L, Moll J, Valtingojer I. Tammaccaro SL, et al. Among authors: guillemot jc. Pharmaceuticals (Basel). 2023 Apr 6;16(4):553. doi: 10.3390/ph16040553. Pharmaceuticals (Basel). 2023. PMID: 37111311 Free PMC article.
AT-752 targets multiple sites and activities on the Dengue virus replication enzyme NS5.
Feracci M, Eydoux C, Fattorini V, Lo Bello L, Gauffre P, Selisko B, Sutto-Ortiz P, Shannon A, Xia H, Shi PY, Noel M, Debart F, Vasseur JJ, Good S, Lin K, Moussa A, Sommadossi JP, Chazot A, Alvarez K, Guillemot JC, Decroly E, Ferron F, Canard B. Feracci M, et al. Among authors: guillemot jc. Antiviral Res. 2023 Apr;212:105574. doi: 10.1016/j.antiviral.2023.105574. Epub 2023 Mar 9. Antiviral Res. 2023. PMID: 36905944
Notch activation shifts the fate decision of senescent progenitors toward myofibrogenesis in human adipose tissue.
Boulet N, Briot A, Jargaud V, Estève D, Rémaury A, Belles C, Viana P, Fontaine J, Murphy L, Déon C, Guillemot M, Pech C, Veeranagouda Y, Didier M, Decaunes P, Mouisel E, Carpéné C, Iacovoni JS, Zakaroff-Girard A, Grolleau JL, Galitzky J, Ledoux S, Guillemot JC, Bouloumié A. Boulet N, et al. Among authors: guillemot jc. Aging Cell. 2023 Mar;22(3):e13776. doi: 10.1111/acel.13776. Epub 2023 Jan 8. Aging Cell. 2023. PMID: 36617688 Free PMC article.
A Versatile Class of 1,4,4-Trisubstituted Piperidines Block Coronavirus Replication In Vitro.
De Castro S, Stevaert A, Maldonado M, Delpal A, Vandeput J, Van Loy B, Eydoux C, Guillemot JC, Decroly E, Gago F, Canard B, Camarasa MJ, Velázquez S, Naesens L. De Castro S, et al. Among authors: guillemot jc. Pharmaceuticals (Basel). 2022 Aug 18;15(8):1021. doi: 10.3390/ph15081021. Pharmaceuticals (Basel). 2022. PMID: 36015168 Free PMC article.
Exploring ITM2A as a new potential target for brain delivery.
Cegarra C, Chaves C, Déon C, Do TM, Dumas B, Frenzel A, Kuhn P, Roudieres V, Guillemot JC, Lesuisse D. Cegarra C, et al. Among authors: guillemot jc. Fluids Barriers CNS. 2022 Mar 21;19(1):25. doi: 10.1186/s12987-022-00321-3. Fluids Barriers CNS. 2022. PMID: 35313913 Free PMC article.
Synthesis, Structure-Activity Relationships, and Antiviral Profiling of 1-Heteroaryl-2-Alkoxyphenyl Analogs as Inhibitors of SARS-CoV-2 Replication.
Bardiot D, Vangeel L, Koukni M, Arzel P, Zwaagstra M, Lyoo H, Wanningen P, Ahmad S, Zhang L, Sun X, Delpal A, Eydoux C, Guillemot JC, Lescrinier E, Klaassen H, Leyssen P, Jochmans D, Castermans K, Hilgenfeld R, Robinson C, Decroly E, Canard B, Snijder EJ, van Hemert MJ, van Kuppeveld F, Chaltin P, Neyts J, De Jonghe S, Marchand A. Bardiot D, et al. Among authors: guillemot jc. Molecules. 2022 Feb 4;27(3):1052. doi: 10.3390/molecules27031052. Molecules. 2022. PMID: 35164317 Free PMC article.
A dual mechanism of action of AT-527 against SARS-CoV-2 polymerase.
Shannon A, Fattorini V, Sama B, Selisko B, Feracci M, Falcou C, Gauffre P, El Kazzi P, Delpal A, Decroly E, Alvarez K, Eydoux C, Guillemot JC, Moussa A, Good SS, La Colla P, Lin K, Sommadossi JP, Zhu Y, Yan X, Shi H, Ferron F, Canard B. Shannon A, et al. Among authors: guillemot jc. Nat Commun. 2022 Feb 2;13(1):621. doi: 10.1038/s41467-022-28113-1. Nat Commun. 2022. PMID: 35110538 Free PMC article.
Simeprevir Potently Suppresses SARS-CoV-2 Replication and Synergizes with Remdesivir.
Lo HS, Hui KPY, Lai HM, He X, Khan KS, Kaur S, Huang J, Li Z, Chan AKN, Cheung HH, Ng KC, Ho JCW, Chen YW, Ma B, Cheung PM, Shin D, Wang K, Lee MH, Selisko B, Eydoux C, Guillemot JC, Canard B, Wu KP, Liang PH, Dikic I, Zuo Z, Chan FKL, Hui DSC, Mok VCT, Wong KB, Mok CKP, Ko H, Aik WS, Chan MCW, Ng WL. Lo HS, et al. Among authors: guillemot jc. ACS Cent Sci. 2021 May 26;7(5):792-802. doi: 10.1021/acscentsci.0c01186. Epub 2021 Apr 15. ACS Cent Sci. 2021. PMID: 34075346 Free PMC article.
Peptidomics of Haemonchus contortus.
Buzy A, Allain C, Harrington J, Lesuisse D, Mikol V, Bruhn DF, Maule AG, Guillemot JC. Buzy A, et al. Among authors: guillemot jc. ACS Omega. 2021 Apr 7;6(15):10288-10305. doi: 10.1021/acsomega.1c00650. eCollection 2021 Apr 20. ACS Omega. 2021. PMID: 34056183 Free PMC article.
111 results