Guilford W - Search Results

1

An aspirin-triggered lipoxin A4 stable analog displays a unique topical anti-inflammatory profile.

Schottelius AJ, Giesen C, Asadullah K, Fierro IM, Colgan SP, Bauman J, Guilford W, Perez HD, Parkinson JF. Schottelius AJ, et al. Among authors: guilford w. J Immunol. 2002 Dec 15;169(12):7063-70. doi: 10.4049/jimmunol.169.12.7063. J Immunol. 2002. PMID: 12471142

2

Novel 3-oxa lipoxin A4 analogues with enhanced chemical and metabolic stability have anti-inflammatory activity in vivo.

Guilford WJ, Bauman JG, Skuballa W, Bauer S, Wei GP, Davey D, Schaefer C, Mallari C, Terkelsen J, Tseng JL, Shen J, Subramanyam B, Schottelius AJ, Parkinson JF. Guilford WJ, et al. J Med Chem. 2004 Apr 8;47(8):2157-65. doi: 10.1021/jm030569l. J Med Chem. 2004. PMID: 15056011

3

Lipoxins and novel 15-epi-lipoxin analogs display potent anti-inflammatory actions after oral administration.

Bannenberg G, Moussignac RL, Gronert K, Devchand PR, Schmidt BA, Guilford WJ, Bauman JG, Subramanyam B, Perez HD, Parkinson JF, Serhan CN. Bannenberg G, et al. Br J Pharmacol. 2004 Sep;143(1):43-52. doi: 10.1038/sj.bjp.0705912. Epub 2004 Aug 9. Br J Pharmacol. 2004. PMID: 15302682 Free PMC article.

4

Second-generation beta-oxidation resistant 3-oxa-lipoxin A4 analogs.

Guilford WJ, Parkinson JF. Guilford WJ, et al. Prostaglandins Leukot Essent Fatty Acids. 2005 Sep-Oct;73(3-4):245-50. doi: 10.1016/j.plefa.2005.05.012. Prostaglandins Leukot Essent Fatty Acids. 2005. PMID: 15985364 Review.

5

Lipoxin a4 analogs attenuate induction of intestinal epithelial proinflammatory gene expression and reduce the severity of dextran sodium sulfate-induced colitis.

Gewirtz AT, Collier-Hyams LS, Young AN, Kucharzik T, Guilford WJ, Parkinson JF, Williams IR, Neish AS, Madara JL. Gewirtz AT, et al. J Immunol. 2002 May 15;168(10):5260-7. doi: 10.4049/jimmunol.168.10.5260. J Immunol. 2002. PMID: 11994483

6

Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism.

Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF. Levy BD, et al. Among authors: guilford wj. FASEB J. 2007 Dec;21(14):3877-84. doi: 10.1096/fj.07-8653com. Epub 2007 Jul 11. FASEB J. 2007. PMID: 17625069 Free PMC article.

7

A beta-oxidation-resistant lipoxin A4 analog treats hapten-induced colitis by attenuating inflammation and immune dysfunction.

Fiorucci S, Wallace JL, Mencarelli A, Distrutti E, Rizzo G, Farneti S, Morelli A, Tseng JL, Suramanyam B, Guilford WJ, Parkinson JF. Fiorucci S, et al. Proc Natl Acad Sci U S A. 2004 Nov 2;101(44):15736-41. doi: 10.1073/pnas.0404722101. Epub 2004 Oct 25. Proc Natl Acad Sci U S A. 2004. PMID: 15505205 Free PMC article.

8

Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase.

Kirkland TA, Adler M, Bauman JG, Chen M, Haeggström JZ, King B, Kochanny MJ, Liang AM, Mendoza L, Phillips GB, Thunnissen M, Trinh L, Whitlow M, Ye B, Ye H, Parkinson J, Guilford WJ. Kirkland TA, et al. Bioorg Med Chem. 2008 May 1;16(9):4963-83. doi: 10.1016/j.bmc.2008.03.042. Epub 2008 Mar 20. Bioorg Med Chem. 2008. PMID: 18394906

9

Development of a homogeneous time-resolved fluorescence leukotriene B4 assay for determining the activity of leukotriene A4 hydrolase.

Liang AM, Claret E, Ouled-Diaf J, Jean A, Vogel D, Light DR, Jones SW, Guilford WJ, Parkinson JF, Snider RM. Liang AM, et al. Among authors: guilford wj. J Biomol Screen. 2007 Jun;12(4):536-45. doi: 10.1177/1087057107299873. Epub 2007 Mar 23. J Biomol Screen. 2007. PMID: 17384330

10

Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase.

Ye B, Bauman J, Chen M, Davey D, Khim SK, King B, Kirkland T, Kochanny M, Liang A, Lentz D, May K, Mendoza L, Phillips G, Selchau V, Schlyer S, Tseng JL, Wei RG, Ye H, Parkinson J, Guilford WJ. Ye B, et al. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3891-4. doi: 10.1016/j.bmcl.2008.06.046. Epub 2008 Jun 18. Bioorg Med Chem Lett. 2008. PMID: 18586492

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