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Comparative study between the anti-P. falciparum activity of triazolopyrimidine, pyrazolopyrimidine and quinoline derivatives and the identification of new PfDHODH inhibitors.
Silveira FF, de Souza JO, Hoelz LVB, Campos VR, Jabor VAP, Aguiar ACC, Nonato MC, Albuquerque MG, Guido RVC, Boechat N, Pinheiro LCS. Silveira FF, et al. Among authors: guido rvc. Eur J Med Chem. 2021 Jan 1;209:112941. doi: 10.1016/j.ejmech.2020.112941. Epub 2020 Oct 21. Eur J Med Chem. 2021. PMID: 33158577
Inhibition of Mycobacterium tuberculosis tyrosine phosphatase PtpA by synthetic chalcones: kinetics, molecular modeling, toxicity and effect on growth.
Mascarello A, Chiaradia LD, Vernal J, Villarino A, Guido RV, Perizzolo P, Poirier V, Wong D, Martins PG, Nunes RJ, Yunes RA, Andricopulo AD, Av-Gay Y, Terenzi H. Mascarello A, et al. Bioorg Med Chem. 2010 Jun 1;18(11):3783-9. doi: 10.1016/j.bmc.2010.04.051. Epub 2010 Apr 21. Bioorg Med Chem. 2010. PMID: 20462762 Free article.
Acridone alkaloids as potent inhibitors of cathepsin V.
Severino RP, Guido RV, Marques EF, Brömme D, da Silva MF, Fernandes JB, Andricopulo AD, Vieira PC. Severino RP, et al. Bioorg Med Chem. 2011 Feb 15;19(4):1477-81. doi: 10.1016/j.bmc.2010.12.056. Epub 2011 Jan 1. Bioorg Med Chem. 2011. PMID: 21277783
New Molecular Targets and Strategies for Antimalarial Discovery.
Aguiar AC, de Sousa LRF, Garcia CRS, Oliva G, Guido RVC. Aguiar AC, et al. Among authors: guido rvc. Curr Med Chem. 2019;26(23):4380-4402. doi: 10.2174/0929867324666170830103003. Curr Med Chem. 2019. PMID: 28875841 Review.
Isolation, Derivative Synthesis, and Structure-Activity Relationships of Antiparasitic Bromopyrrole Alkaloids from the Marine Sponge Tedania brasiliensis.
Parra LLL, Bertonha AF, Severo IRM, Aguiar ACC, de Souza GE, Oliva G, Guido RVC, Grazzia N, Costa TR, Miguel DC, Gadelha FR, Ferreira AG, Hajdu E, Romo D, Berlinck RGS. Parra LLL, et al. Among authors: guido rvc. J Nat Prod. 2018 Jan 26;81(1):188-202. doi: 10.1021/acs.jnatprod.7b00876. Epub 2018 Jan 3. J Nat Prod. 2018. PMID: 29297684 Free PMC article.
Synthesis, Profiling, and in Vivo Evaluation of Cyclopeptides Containing N-Methyl Amino Acids as Antiplasmodial Agents.
Fagundez C, Sellanes D, Peña S, Scarone L, Aguiar ACC, de Souza JO, Guido RVC, Stewart L, Yardley V, Ottilie S, Winzeler EA, Gamo FJ, Sanz LM, Serra GL. Fagundez C, et al. Among authors: guido rvc. ACS Med Chem Lett. 2018 Dec 26;10(1):137-141. doi: 10.1021/acsmedchemlett.8b00543. eCollection 2019 Jan 10. ACS Med Chem Lett. 2018. PMID: 30655961 Free PMC article.
79 results