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CRISPR screens reveal genetic determinants of PARP inhibitor sensitivity and resistance in prostate cancer.
Tsujino T, Takai T, Hinohara K, Gui F, Tsutsumi T, Bai X, Miao C, Feng C, Gui B, Sztupinszki Z, Simoneau A, Xie N, Fazli L, Dong X, Azuma H, Choudhury AD, Mouw KW, Szallasi Z, Zou L, Kibel AS, Jia L. Tsujino T, et al. Among authors: gui f, gui b. Nat Commun. 2023 Jan 17;14(1):252. doi: 10.1038/s41467-023-35880-y. Nat Commun. 2023. PMID: 36650183 Free PMC article.
Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors.
Jiang J, Gui F, He Z, Li L, Li Y, Li S, Wu X, Deng Z, Sun X, Huang X, Huang W, Han S, Zhang T, Wang Z, Jiao B, Song S, Wang H, Chen L, Zhou D, Liu Q, Ren R, Zhang J, Deng X. Jiang J, et al. Among authors: gui f. Cancer Res. 2017 Jan 1;77(1):175-186. doi: 10.1158/0008-5472.CAN-16-1038. Epub 2016 Oct 10. Cancer Res. 2017. PMID: 27758886
A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.
Lu Y, Fan Z, Zhu SJ, Huang X, Zhuang Z, Li Y, Deng Z, Gao L, Hong X, Zhang T, Li L, Sun X, Huang W, Zhang J, Liu Y, Zhang B, Jiang J, Gui F, Wang Z, Li Q, Song S, Huang X, Wu Q, Chen L, Zhou D, Zhang J, Yun CH, Chen L, Deng X. Lu Y, et al. Among authors: gui f. EMBO Mol Med. 2022 Jan 11;14(1):e14296. doi: 10.15252/emmm.202114296. Epub 2021 Nov 30. EMBO Mol Med. 2022. PMID: 34845836 Free PMC article.
The aldolase inhibitor aldometanib mimics glucose starvation to activate lysosomal AMPK.
Zhang CS, Li M, Wang Y, Li X, Zong Y, Long S, Zhang M, Feng JW, Wei X, Liu YH, Zhang B, Wu J, Zhang C, Lian W, Ma T, Tian X, Qu Q, Yu Y, Xiong J, Liu DT, Wu Z, Zhu M, Xie C, Wu Y, Xu Z, Yang C, Chen J, Huang G, He Q, Huang X, Zhang L, Sun X, Liu Q, Ghafoor A, Gui F, Zheng K, Wang W, Wang ZC, Yu Y, Zhao Q, Lin SY, Wang ZX, Piao HL, Deng X, Lin SC. Zhang CS, et al. Among authors: gui f. Nat Metab. 2022 Oct;4(10):1369-1401. doi: 10.1038/s42255-022-00640-7. Epub 2022 Oct 10. Nat Metab. 2022. PMID: 36217034 Free PMC article.
113 results