Guguen-Guillouzo C - Search Results

1

Synthesis and kinase inhibitory activity of novel substituted indigoids.

Beauchard A, Laborie H, Rouillard H, Lozach O, Ferandin Y, Le Guével R, Guguen-Guillouzo C, Meijer L, Besson T, Thiéry V. Beauchard A, et al. Bioorg Med Chem. 2009 Sep 1;17(17):6257-63. doi: 10.1016/j.bmc.2009.07.051. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19665384

2

Novel tetrahydropyrido[1,2-a]isoindolone derivatives (valmerins): potent cyclin-dependent kinase/glycogen synthase kinase 3 inhibitors with antiproliferative activities and antitumor effects in human tumor xenografts.

Boulahjar R, Ouach A, Matteo C, Bourg S, Ravache M, le Guével R, Marionneau S, Oullier T, Lozach O, Meijer L, Guguen-Guillouzo C, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. J Med Chem. 2012 Nov 26;55(22):9589-606. doi: 10.1021/jm3008536. Epub 2012 Nov 1. J Med Chem. 2012. PMID: 23083119

3

Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

Boulahjar R, Ouach A, Bourg S, Bonnet P, Lozach O, Meijer L, Guguen-Guillouzo C, Le Guevel R, Lazar S, Akssira M, Troin Y, Guillaumet G, Routier S. Boulahjar R, et al. Eur J Med Chem. 2015 Aug 28;101:274-87. doi: 10.1016/j.ejmech.2015.06.046. Epub 2015 Jun 27. Eur J Med Chem. 2015. PMID: 26142492 Free article.

4

Novel optimization of valmerins (tetrahydropyrido[1,2-a]isoindolones) as potent dual CDK5/GSK3 inhibitors.

Ouach A, Boulahjar R, Vala C, Bourg S, Bonnet P, Guguen-Guillouzo C, Ravache M, Le Guevel R, Lozach O, Lazar S, Troin Y, Meijer L, Ruchaud S, Akssira M, Guillaumet G, Routier S. Ouach A, et al. Eur J Med Chem. 2016 Jun 10;115:311-25. doi: 10.1016/j.ejmech.2016.02.072. Epub 2016 Mar 2. Eur J Med Chem. 2016. PMID: 27019296

5

Cytotoxic evaluation of sarcodifurines A and B, two novel dihydrofuroquinolines from Sarcomelicope follicularis (Rutaceae).

Chosson E, Guguen-Guillouzo C, Glaise D, Picot L, Seguin E, Besson T. Chosson E, et al. J Enzyme Inhib Med Chem. 2008 Oct;23(5):704-7. doi: 10.1080/14756360802208111. J Enzyme Inhib Med Chem. 2008. PMID: 18608759

6

Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration.

Loyer P, Glaise D, Cariou S, Baffet G, Meijer L, Guguen-Guillouzo C. Loyer P, et al. J Biol Chem. 1994 Jan 28;269(4):2491-500. J Biol Chem. 1994. PMID: 8300575 Free article.

7

Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye.

Pernelle K, Le Guevel R, Glaise D, Stasio CG, Le Charpentier T, Bouaita B, Corlu A, Guguen-Guillouzo C. Pernelle K, et al. Toxicol Appl Pharmacol. 2011 Aug 1;254(3):256-66. doi: 10.1016/j.taap.2011.04.018. Epub 2011 May 4. Toxicol Appl Pharmacol. 2011. PMID: 21569786

8

Rho-kinase/myosin light chain kinase pathway plays a key role in the impairment of bile canaliculi dynamics induced by cholestatic drugs.

Sharanek A, Burban A, Burbank M, Le Guevel R, Li R, Guillouzo A, Guguen-Guillouzo C. Sharanek A, et al. Sci Rep. 2016 May 12;6:24709. doi: 10.1038/srep24709. Sci Rep. 2016. PMID: 27169750 Free PMC article.

9

Electrochemical synthesis and characterisation of alternating tripyridyl-dipyrrole molecular strands with multiple nitrogen-based donor-acceptor binding sites.

Tabatchnik-Rebillon A, Aubé C, Bakkali H, Delaunay T, Manh GT, Blot V, Thobie-Gautier C, Renault E, Soulard M, Planchat A, Le Questel JY, Le Guével R, Guguen-Guillouzo C, Kauffmann B, Ferrand Y, Huc I, Urgin K, Condon S, Léonel E, Evain M, Lebreton J, Jacquemin D, Pipelier M, Dubreuil D. Tabatchnik-Rebillon A, et al. Chemistry. 2010 Oct 18;16(39):11876-89. doi: 10.1002/chem.201000859. Chemistry. 2010. PMID: 20839373

10

In-Depth Proteome Analysis Highlights HepaRG Cells as a Versatile Cell System Surrogate for Primary Human Hepatocytes.

Tascher G, Burban A, Camus S, Plumel M, Chanon S, Le Guevel R, Shevchenko V, Van Dorsselaer A, Lefai E, Guguen-Guillouzo C, Bertile F. Tascher G, et al. Among authors: guguen guillouzo c. Cells. 2019 Feb 21;8(2):192. doi: 10.3390/cells8020192. Cells. 2019. PMID: 30795634 Free PMC article.

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