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A genome-wide association study of post-traumatic stress disorder identifies the retinoid-related orphan receptor alpha (RORA) gene as a significant risk locus.
Logue MW, Baldwin C, Guffanti G, Melista E, Wolf EJ, Reardon AF, Uddin M, Wildman D, Galea S, Koenen KC, Miller MW. Logue MW, et al. Among authors: guffanti g. Mol Psychiatry. 2013 Aug;18(8):937-42. doi: 10.1038/mp.2012.113. Epub 2012 Aug 7. Mol Psychiatry. 2013. PMID: 22869035 Free PMC article.
Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.
Duncan LE, Ratanatharathorn A, Aiello AE, Almli LM, Amstadter AB, Ashley-Koch AE, Baker DG, Beckham JC, Bierut LJ, Bisson J, Bradley B, Chen CY, Dalvie S, Farrer LA, Galea S, Garrett ME, Gelernter JE, Guffanti G, Hauser MA, Johnson EO, Kessler RC, Kimbrel NA, King A, Koen N, Kranzler HR, Logue MW, Maihofer AX, Martin AR, Miller MW, Morey RA, Nugent NR, Rice JP, Ripke S, Roberts AL, Saccone NL, Smoller JW, Stein DJ, Stein MB, Sumner JA, Uddin M, Ursano RJ, Wildman DE, Yehuda R, Zhao H, Daly MJ, Liberzon I, Ressler KJ, Nievergelt CM, Koenen KC. Duncan LE, et al. Among authors: guffanti g. Mol Psychiatry. 2018 Mar;23(3):666-673. doi: 10.1038/mp.2017.77. Epub 2017 Apr 25. Mol Psychiatry. 2018. PMID: 28439101 Free PMC article.
Polygenic risk associated with post-traumatic stress disorder onset and severity.
Misganaw B, Guffanti G, Lori A, Abu-Amara D, Flory JD; SBPBC; Mueller S, Yehuda R, Jett M, Marmar CR, Ressler KJ, Doyle FJ 3rd. Misganaw B, et al. Among authors: guffanti g. Transl Psychiatry. 2019 Jun 7;9(1):165. doi: 10.1038/s41398-019-0497-3. Transl Psychiatry. 2019. PMID: 31175274 Free PMC article.
Multi-omic biomarker identification and validation for diagnosing warzone-related post-traumatic stress disorder.
Dean KR, Hammamieh R, Mellon SH, Abu-Amara D, Flory JD, Guffanti G, Wang K, Daigle BJ Jr, Gautam A, Lee I, Yang R, Almli LM, Bersani FS, Chakraborty N, Donohue D, Kerley K, Kim TK, Laska E, Young Lee M, Lindqvist D, Lori A, Lu L, Misganaw B, Muhie S, Newman J, Price ND, Qin S, Reus VI, Siegel C, Somvanshi PR, Thakur GS, Zhou Y; PTSD Systems Biology Consortium; Hood L, Ressler KJ, Wolkowitz OM, Yehuda R, Jett M, Doyle FJ 3rd, Marmar C. Dean KR, et al. Among authors: guffanti g. Mol Psychiatry. 2020 Dec;25(12):3337-3349. doi: 10.1038/s41380-019-0496-z. Epub 2019 Sep 10. Mol Psychiatry. 2020. PMID: 31501510 Free PMC article.
66 results