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A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss.
Peixoto Pinheiro B, Müller M, Bös M, Guezguez J, Burnet M, Tornincasa M, Rizzetto R, Rolland JF, Liberati C, Lohmer S, Adel Y, Löwenheim H. Peixoto Pinheiro B, et al. Among authors: guezguez j. Cell Death Dis. 2022 Jul 11;13(7):595. doi: 10.1038/s41419-022-04915-5. Cell Death Dis. 2022. PMID: 35817766 Free PMC article.
Penetration, distribution, and elimination of remofuscin/soraprazan in Stargardt mouse eyes following a single intravitreal injection using pharmacokinetics and transmission electron microscopic autoradiography: Implication for the local treatment of Stargardt's disease and dry age-related macular degeneration.
Julien-Schraermeyer S, Illing B, Tschulakow A, Taubitz T, Guezguez J, Burnet M, Schraermeyer U. Julien-Schraermeyer S, et al. Among authors: guezguez j. Pharmacol Res Perspect. 2020 Dec;8(6):e00683. doi: 10.1002/prp2.683. Pharmacol Res Perspect. 2020. PMID: 33164337 Free PMC article.
Isostearic acid is an active component of imiquimod formulations used to induce psoriaform disease models.
Straß S, Geiger J, Martorelli M, Geiger S, Cloos N, Keppler M, Fischer T, Riexinger L, Schwamborn A, Guezguez J, Späth N, Cruces S, Guse JH, Sandri TL, Burnet M, Laufer S. Straß S, et al. Among authors: guezguez j. Inflammopharmacology. 2023 Apr;31(2):799-812. doi: 10.1007/s10787-023-01175-3. Epub 2023 Mar 21. Inflammopharmacology. 2023. PMID: 36943539
Pharmacokinetic Optimization of Small Molecule Janus Kinase 3 Inhibitors to Target Immune Cells.
Laux J, Forster M, Riexinger L, Schwamborn A, Guezguez J, Pokoj C, Kudolo M, Berger LM, Knapp S, Schollmeyer D, Guse J, Burnet M, Laufer SA. Laux J, et al. Among authors: guezguez j. ACS Pharmacol Transl Sci. 2022 Jul 14;5(8):573-602. doi: 10.1021/acsptsci.2c00054. eCollection 2022 Aug 12. ACS Pharmacol Transl Sci. 2022. PMID: 35983274 Free PMC article.
12 results