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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1.
Jung SM, Hung CM, Hildebrand SR, Sanchez-Gurmaches J, Martinez-Pastor B, Gengatharan JM, Wallace M, Mukhopadhyay D, Martinez Calejman C, Luciano AK, Hsiao WY, Tang Y, Li H, Daniels DL, Mostoslavsky R, Metallo CM, Guertin DA. Jung SM, et al. Among authors: guertin da. Mol Cell. 2019 Aug 22;75(4):807-822.e8. doi: 10.1016/j.molcel.2019.07.023. Mol Cell. 2019. PMID: 31442424 Free PMC article.
mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.
Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. Peterson TR, et al. Among authors: guertin da. Cell. 2011 Aug 5;146(3):408-20. doi: 10.1016/j.cell.2011.06.034. Cell. 2011. PMID: 21816276 Free PMC article.
mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis.
Kalaitzidis D, Sykes SM, Wang Z, Punt N, Tang Y, Ragu C, Sinha AU, Lane SW, Souza AL, Clish CB, Anastasiou D, Gilliland DG, Scadden DT, Guertin DA, Armstrong SA. Kalaitzidis D, et al. Among authors: guertin da. Cell Stem Cell. 2012 Sep 7;11(3):429-39. doi: 10.1016/j.stem.2012.06.009. Cell Stem Cell. 2012. PMID: 22958934 Free PMC article.
mTOR-dependent cell survival mechanisms.
Hung CM, Garcia-Haro L, Sparks CA, Guertin DA. Hung CM, et al. Among authors: guertin da. Cold Spring Harb Perspect Biol. 2012 Dec 1;4(12):a008771. doi: 10.1101/cshperspect.a008771. Cold Spring Harb Perspect Biol. 2012. PMID: 23124837 Free PMC article. Review.
Adipocyte lineages: tracing back the origins of fat.
Sanchez-Gurmaches J, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: guertin da. Biochim Biophys Acta. 2014 Mar;1842(3):340-51. doi: 10.1016/j.bbadis.2013.05.027. Epub 2013 Jun 4. Biochim Biophys Acta. 2014. PMID: 23747579 Free PMC article. Review.
mTORC1 gRABs the Golgi.
Sanchez-Gurmaches J, Guertin DA. Sanchez-Gurmaches J, et al. Among authors: guertin da. Cancer Cell. 2014 Nov 10;26(5):601-3. doi: 10.1016/j.ccell.2014.10.011. Epub 2014 Nov 10. Cancer Cell. 2014. PMID: 25517745 Free article.
74 results