Guertin DA - Search Results

1

Rictor/mTORC2 loss in the Myf5 lineage reprograms brown fat metabolism and protects mice against obesity and metabolic disease.

Hung CM, Calejman CM, Sanchez-Gurmaches J, Li H, Clish CB, Hettmer S, Wagers AJ, Guertin DA. Hung CM, et al. Among authors: guertin da. Cell Rep. 2014 Jul 10;8(1):256-71. doi: 10.1016/j.celrep.2014.06.007. Epub 2014 Jul 4. Cell Rep. 2014. PMID: 25001283 Free PMC article.

2

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex.

Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Sarbassov DD, et al. Among authors: guertin da. Science. 2005 Feb 18;307(5712):1098-101. doi: 10.1126/science.1106148. Science. 2005. PMID: 15718470

3

Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1.

Guertin DA, Stevens DM, Thoreen CC, Burds AA, Kalaany NY, Moffat J, Brown M, Fitzgerald KJ, Sabatini DM. Guertin DA, et al. Dev Cell. 2006 Dec;11(6):859-71. doi: 10.1016/j.devcel.2006.10.007. Dev Cell. 2006. PMID: 17141160 Free article.

4

Defining the role of mTOR in cancer.

Guertin DA, Sabatini DM. Guertin DA, et al. Cancer Cell. 2007 Jul;12(1):9-22. doi: 10.1016/j.ccr.2007.05.008. Cancer Cell. 2007. PMID: 17613433 Free article. Review.

5

mTOR complex 2 is required for the development of prostate cancer induced by Pten loss in mice.

Guertin DA, Stevens DM, Saitoh M, Kinkel S, Crosby K, Sheen JH, Mullholland DJ, Magnuson MA, Wu H, Sabatini DM. Guertin DA, et al. Cancer Cell. 2009 Feb 3;15(2):148-59. doi: 10.1016/j.ccr.2008.12.017. Cancer Cell. 2009. PMID: 19185849 Free PMC article.

6

Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapy.

Sparks CA, Guertin DA. Sparks CA, et al. Among authors: guertin da. Oncogene. 2010 Jul 1;29(26):3733-44. doi: 10.1038/onc.2010.139. Epub 2010 Apr 26. Oncogene. 2010. PMID: 20418915 Free PMC article. Review.

7

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

Peterson TR, Sengupta SS, Harris TE, Carmack AE, Kang SA, Balderas E, Guertin DA, Madden KL, Carpenter AE, Finck BN, Sabatini DM. Peterson TR, et al. Among authors: guertin da. Cell. 2011 Aug 5;146(3):408-20. doi: 10.1016/j.cell.2011.06.034. Cell. 2011. PMID: 21816276 Free PMC article.

8

Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics.

Li H, Cotton JL, Guertin DA. Li H, et al. Among authors: guertin da. Methods Mol Biol. 2012;821:329-47. doi: 10.1007/978-1-61779-430-8_21. Methods Mol Biol. 2012. PMID: 22125076

9

Sarcomas induced in discrete subsets of prospectively isolated skeletal muscle cells.

Hettmer S, Liu J, Miller CM, Lindsay MC, Sparks CA, Guertin DA, Bronson RT, Langenau DM, Wagers AJ. Hettmer S, et al. Among authors: guertin da. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20002-7. doi: 10.1073/pnas.1111733108. Epub 2011 Nov 30. Proc Natl Acad Sci U S A. 2011. PMID: 22135462 Free PMC article.

10

Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity.

Lamming DW, Ye L, Katajisto P, Goncalves MD, Saitoh M, Stevens DM, Davis JG, Salmon AB, Richardson A, Ahima RS, Guertin DA, Sabatini DM, Baur JA. Lamming DW, et al. Among authors: guertin da. Science. 2012 Mar 30;335(6076):1638-43. doi: 10.1126/science.1215135. Science. 2012. PMID: 22461615 Free PMC article.

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