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A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells.
Machado PHA, Paixão DA, Lino RC, de Souza TR, de Souza Bontempo NJ, Sousa LM, Van Petten de Vasconcelos Azevedo F, Orsolin PC, Lima PMAP, Martins IC, da Costa Guerra JF, Teixeira SC, Araújo TG, Goulart LR, Morelli S, Guerra W, de Oliveira Júnior RJ. Machado PHA, et al. Among authors: guerra w. Sci Rep. 2021 Dec 27;11(1):24450. doi: 10.1038/s41598-021-03909-1. Sci Rep. 2021. PMID: 34961767 Free PMC article.
Novel copper(II) complexes with hydrazides and heterocyclic bases: Synthesis, structure and biological studies.
Paixão DA, Marzano IM, Jaimes EHL, Pivatto M, Campos DL, Pavan FR, Deflon VM, Maia PIDS, Da Costa Ferreira AM, Uehara IA, Silva MJB, Botelho FV, Pereira-Maia EC, Guilardi S, Guerra W. Paixão DA, et al. Among authors: guerra w. J Inorg Biochem. 2017 Jul;172:138-146. doi: 10.1016/j.jinorgbio.2017.04.024. Epub 2017 Apr 26. J Inorg Biochem. 2017. PMID: 28463762
Three new platinum complexes containing fluoroquinolones and DMSO: Cytotoxicity and evaluation against drug-resistant tuberculosis.
de Oliveira LP, Carneiro ZA, Ribeiro CM, Lima MF, Paixão DA, Pivatto M, de Souza MVN, Teixeira LR, Lopes CD, de Albuquerque S, Pavan FR, Guerra W. de Oliveira LP, et al. Among authors: guerra w. J Inorg Biochem. 2018 Jun;183:77-83. doi: 10.1016/j.jinorgbio.2018.03.010. Epub 2018 Mar 16. J Inorg Biochem. 2018. PMID: 29567518
In vitro anti-Trypanosoma cruzi activity of ternary copper(II) complexes and in vivo evaluation of the most promising complex.
Paixão DA, Lopes CD, Carneiro ZA, Sousa LM, de Oliveira LP, Lopes NP, Pivatto M, Chaves JDS, de Almeida MV, Ellena J, Moreira MB, Netto AVG, de Oliveira RJ, Guilardi S, de Albuquerque S, Guerra W. Paixão DA, et al. Among authors: guerra w. Biomed Pharmacother. 2019 Jan;109:157-166. doi: 10.1016/j.biopha.2018.10.057. Epub 2018 Nov 2. Biomed Pharmacother. 2019. PMID: 30396072 Free article.
Action of copper(II) complex with β-diketone and 1,10-phenanthroline (CBP-01) on sarcoma cells and biological effects under cell death.
Polloni L, Seni Silva AC, Teixeira SC, Azevedo FVPV, Zóia MAP, da Silva MS, Lima PMAP, Correia LIV, do Couto Almeida J, da Silva CV, Rodrigues Ávila VM, Goulart LRF, Morelli S, Guerra W, Oliveira Júnior RJ. Polloni L, et al. Among authors: guerra w. Biomed Pharmacother. 2019 Apr;112:108586. doi: 10.1016/j.biopha.2019.01.047. Epub 2019 Feb 18. Biomed Pharmacother. 2019. PMID: 30784909 Free article.
A Ternary Copper (II) Complex with 4-Fluorophenoxyacetic Acid Hydrazide in Combination with Antibiotics Exhibits Positive Synergistic Effect against Salmonella Typhimurium.
Monteiro GP, Melo RT, Guidotti-Takeuchi M, Dumont CF, Ribeiro RAC, Guerra W, Ramos LMS, Paixão DA, Santos FALD, Rodrigues DDP, Boleij P, Hoepers PG, Rossi DA. Monteiro GP, et al. Among authors: guerra w. Antibiotics (Basel). 2022 Mar 15;11(3):388. doi: 10.3390/antibiotics11030388. Antibiotics (Basel). 2022. PMID: 35326852 Free PMC article.
Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound.
Bontempo NJS, Paixão DA, Lima PMAP, Barros DCT, Borges DS, Orsolin PC, Martins IC, Machado PHA, Lino RC, Souza TR, Ramos LMS, Teixeira SC, Siqueira RP, Goulart Filho LR, Guerra W, Oliveira Júnior RJ, Araújo TG. Bontempo NJS, et al. Among authors: guerra w. Molecules. 2022 Oct 20;27(20):7097. doi: 10.3390/molecules27207097. Molecules. 2022. PMID: 36296690 Free PMC article.
A new copper(II) complex containing long-chain aliphatic hydrazide and 1,10-phenanthroline upregulates ADP hydrolysis in triple-negative breast cancer cells.
Ferreira HSV, Ramos LMS, Silva FC, Alves DL, de Menezes Pereira G, de Oliveira Santiago PH, de Almeida AM, Ellena J, Corbi PP, Oliveira CG, de Almeida MV, Fürstenau CR, Borges DS, Siqueira RP, Guerra W, Araújo TG. Ferreira HSV, et al. Among authors: guerra w. J Inorg Biochem. 2024 Jun;255:112524. doi: 10.1016/j.jinorgbio.2024.112524. Epub 2024 Mar 16. J Inorg Biochem. 2024. PMID: 38507993
Correlation between DNA interactions and cytotoxic activity of four new ternary compounds of copper(II) with N-donor heterocyclic ligands.
Silva PP, Guerra W, Dos Santos GC, Fernandes NG, Silveira JN, da Costa Ferreira AM, Bortolotto T, Terenzi H, Bortoluzzi AJ, Neves A, Pereira-Maia EC. Silva PP, et al. Among authors: guerra w. J Inorg Biochem. 2014 Mar;132:67-76. doi: 10.1016/j.jinorgbio.2013.09.014. Epub 2013 Oct 5. J Inorg Biochem. 2014. PMID: 24144484
71 results