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Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.
Schmelz K, Toedling J, Huska M, Cwikla MC, Kruetzfeldt LM, Proba J, Ambros PF, Ambros IM, Boral S, Lodrini M, Chen CY, Burkert M, Guergen D, Szymansky A, Astrahantseff K, Kuenkele A, Haase K, Fischer M, Deubzer HE, Hertwig F, Hundsdoerfer P, Henssen AG, Schwarz RF, Schulte JH, Eggert A. Schmelz K, et al. Among authors: guergen d. Nat Commun. 2021 Nov 23;12(1):6804. doi: 10.1038/s41467-021-26870-z. Nat Commun. 2021. PMID: 34815394 Free PMC article.
Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt B, Zasada C, Baum K, Wuenschel J, Mastrobuoni G, Lodrini M, Astrahantseff K, Winkler A, Schulte JH, Finkler S, Forbes M, Hundsdoerfer P, Guergen D, Hoffmann J, Wolf J, Eggert A, Kempa S, Deubzer HE. Arlt B, et al. Among authors: guergen d. Int J Cancer. 2021 Mar 1;148(5):1219-1232. doi: 10.1002/ijc.33423. Epub 2020 Dec 17. Int J Cancer. 2021. PMID: 33284994 Free article.