Guerard M - Search Results

1

Discovery of Risdiplam, a Selective Survival of Motor Neuron-2 ( SMN2) Gene Splicing Modifier for the Treatment of Spinal Muscular Atrophy (SMA).

Ratni H, Ebeling M, Baird J, Bendels S, Bylund J, Chen KS, Denk N, Feng Z, Green L, Guerard M, Jablonski P, Jacobsen B, Khwaja O, Kletzl H, Ko CP, Kustermann S, Marquet A, Metzger F, Mueller B, Naryshkin NA, Paushkin SV, Pinard E, Poirier A, Reutlinger M, Weetall M, Zeller A, Zhao X, Mueller L. Ratni H, et al. Among authors: guerard m. J Med Chem. 2018 Aug 9;61(15):6501-6517. doi: 10.1021/acs.jmedchem.8b00741. Epub 2018 Jul 25. J Med Chem. 2018. PMID: 30044619

2

Quantitative assessment of the dose-response of alkylating agents in DNA repair proficient and deficient ames tester strains.

Tang L, Guérard M, Zeller A. Tang L, et al. Among authors: guerard m. Environ Mol Mutagen. 2014 Jan;55(1):15-23. doi: 10.1002/em.21825. Epub 2013 Nov 23. Environ Mol Mutagen. 2014. PMID: 24273186

3

An appraisal of critical effect sizes for the benchmark dose approach to assess dose-response relationships in genetic toxicology.

Zeller A, Duran-Pacheco G, Guérard M. Zeller A, et al. Among authors: guerard m. Arch Toxicol. 2017 Dec;91(12):3799-3807. doi: 10.1007/s00204-017-2037-3. Epub 2017 Aug 10. Arch Toxicol. 2017. PMID: 28799093

4

Correction to: An appraisal of critical effect sizes for the benchmark dose approach to assess dose-response relationships in genetic toxicology.

Zeller A, Duran-Pacheco G, Guérard M. Zeller A, et al. Among authors: guerard m. Arch Toxicol. 2017 Dec;91(12):3809. doi: 10.1007/s00204-017-2110-y. Arch Toxicol. 2017. PMID: 29128924

5

In vitro genotoxicity of neutral red after photo-activation and metabolic activation in the Ames test, the micronucleus test and the comet assay.

Guérard M, Zeller A, Singer T, Gocke E. Guérard M, et al. Mutat Res. 2012 Jul 4;746(1):15-20. doi: 10.1016/j.mrgentox.2012.01.012. Epub 2012 Mar 5. Mutat Res. 2012. PMID: 22414563

6

Genotoxicity testing of peptides: folate deprivation as a marker of exaggerated pharmacology.

Guérard M, Zeller A, Festag M, Schubert C, Singer T, Müller L. Guérard M, et al. Toxicol Appl Pharmacol. 2014 Sep 15;279(3):419-427. doi: 10.1016/j.taap.2014.06.022. Epub 2014 Jul 2. Toxicol Appl Pharmacol. 2014. PMID: 24997324

7

DNA Damage Response of 4-Chloro-Ortho-Toluidine in Various Rat Tissues.

Guérard M, Marchand C, Funk J, Christen F, Winter M, Zeller A. Guérard M, et al. Toxicol Sci. 2018 Jun 1;163(2):516-524. doi: 10.1093/toxsci/kfy054. Toxicol Sci. 2018. PMID: 29579244

8

Genotoxicity profile of azidothymidine in vitro.

Zeller A, Koenig J, Schmitt G, Singer T, Guérard M. Zeller A, et al. Among authors: guerard m. Toxicol Sci. 2013 Oct;135(2):317-27. doi: 10.1093/toxsci/kft149. Epub 2013 Jun 28. Toxicol Sci. 2013. PMID: 23811827

9

A proposal for a novel rationale for critical effect size in dose-response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.

Zeller A, Tang L, Dertinger SD, Funk J, Duran-Pacheco G, Guérard M. Zeller A, et al. Among authors: guerard m. Mutagenesis. 2016 May;31(3):239-53. doi: 10.1093/mutage/gev077. Epub 2015 Nov 20. Mutagenesis. 2016. PMID: 26590612

10

Assessment of the genotoxic potential of azidothymidine in the comet, micronucleus, and Pig-a assay.

Guérard M, Koenig J, Festag M, Dertinger SD, Singer T, Schmitt G, Zeller A. Guérard M, et al. Toxicol Sci. 2013 Oct;135(2):309-16. doi: 10.1093/toxsci/kft148. Epub 2013 Jun 28. Toxicol Sci. 2013. PMID: 23811826

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