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Intrinsic cell-penetrating activity propels Omomyc from proof of concept to viable anti-MYC therapy.
Beaulieu ME, Jauset T, Massó-Vallés D, Martínez-Martín S, Rahl P, Maltais L, Zacarias-Fluck MF, Casacuberta-Serra S, Serrano Del Pozo E, Fiore C, Foradada L, Cano VC, Sánchez-Hervás M, Guenther M, Romero Sanz E, Oteo M, Tremblay C, Martín G, Letourneau D, Montagne M, Morcillo Alonso MÁ, Whitfield JR, Lavigne P, Soucek L. Beaulieu ME, et al. Among authors: guenther m. Sci Transl Med. 2019 Mar 20;11(484):eaar5012. doi: 10.1126/scitranslmed.aar5012. Sci Transl Med. 2019. PMID: 30894502 Free PMC article.
Genome-wide localization of small molecules.
Anders L, Guenther MG, Qi J, Fan ZP, Marineau JJ, Rahl PB, Lovén J, Sigova AA, Smith WB, Lee TI, Bradner JE, Young RA. Anders L, et al. Nat Biotechnol. 2014 Jan;32(1):92-6. doi: 10.1038/nbt.2776. Epub 2013 Dec 15. Nat Biotechnol. 2014. PMID: 24336317 Free PMC article.
Transcription. Repressive transcription.
Guenther MG, Young RA. Guenther MG, et al. Science. 2010 Jul 9;329(5988):150-1. doi: 10.1126/science.1193995. Science. 2010. PMID: 20616255 Free PMC article. No abstract available.
Global and Hox-specific roles for the MLL1 methyltransferase.
Guenther MG, Jenner RG, Chevalier B, Nakamura T, Croce CM, Canaani E, Young RA. Guenther MG, et al. Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8603-8. doi: 10.1073/pnas.0503072102. Epub 2005 Jun 7. Proc Natl Acad Sci U S A. 2005. PMID: 15941828 Free PMC article.
Core transcriptional regulatory circuitry in human embryonic stem cells.
Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R, Young RA. Boyer LA, et al. Among authors: guenther mg. Cell. 2005 Sep 23;122(6):947-56. doi: 10.1016/j.cell.2005.08.020. Cell. 2005. PMID: 16153702 Free PMC article.
Grounded: transcriptional pausing in naive mESCs.
Guenther MG, Young RA. Guenther MG, et al. Cell Stem Cell. 2012 May 4;10(5):484-5. doi: 10.1016/j.stem.2012.04.016. Cell Stem Cell. 2012. PMID: 22560069 Free article.
206 results