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CX3CL1 homo-oligomerization drives cell-to-cell adherence.
Sci Rep. 2020 Jun 3;10(1):9069. doi: 10.1038/s41598-020-65988-w.
Sci Rep. 2020.
PMID: 32494000
Free PMC article.
CX3CL1, a chemokine finely tuned to adhesion: critical roles of the stalk glycosylation and the membrane domain.
Ostuni MA, Guellec J, Hermand P, Durand P, Combadière C, Pincet F, Deterre P.
Ostuni MA, et al. Among authors: guellec j.
Biol Open. 2014 Nov 13;3(12):1173-82. doi: 10.1242/bio.20149845.
Biol Open. 2014.
PMID: 25395671
Free PMC article.
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Molecular model of the ferroportin intracellular gate and implications for the human iron transport cycle and hemochromatosis type 4A.
Guellec J, Elbahnsi A, Tertre ML, Uguen K, Gourlaouen I, Férec C, Ka C, Callebaut I, Gac GL.
Guellec J, et al.
FASEB J. 2019 Dec;33(12):14625-14635. doi: 10.1096/fj.201901857R. Epub 2019 Nov 5.
FASEB J. 2019.
PMID: 31690120
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The SLC40A1 R178Q mutation is a recurrent cause of hemochromatosis and is associated with a novel pathogenic mechanism.
Ka C, Guellec J, Pepermans X, Kannengiesser C, Ged C, Wuyts W, Cassiman D, de Ledinghen V, Varet B, de Kerguenec C, Oudin C, Gourlaouen I, Lefebvre T, Férec C, Callebaut I, Le Gac G.
Ka C, et al. Among authors: guellec j.
Haematologica. 2018 Nov;103(11):1796-1805. doi: 10.3324/haematol.2018.189845. Epub 2018 Jul 12.
Haematologica. 2018.
PMID: 30002125
Free PMC article.
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Deciphering the molecular basis of ferroportin resistance to hepcidin: Structure/function analysis of rare SLC40A1 missense mutations found in suspected hemochromatosis type 4 patients.
Le Tertre M, Ka C, Guellec J, Gourlaouen I, Férec C, Callebaut I, Le Gac G.
Le Tertre M, et al. Among authors: guellec j.
Transfus Clin Biol. 2017 Nov;24(4):462-467. doi: 10.1016/j.tracli.2017.07.002. Epub 2017 Aug 18.
Transfus Clin Biol. 2017.
PMID: 28826751
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Evaluation of aminopyrrolidine amide to improve chloride transport in CFTR-defective cells.
Huguet F, Guellec J, Kerbiriou M, Gandy M, Thomas J, Férec C, Benz N, Trouvé P.
Huguet F, et al. Among authors: guellec j.
Bioorg Med Chem Lett. 2022 Sep 15;72:128866. doi: 10.1016/j.bmcl.2022.128866. Epub 2022 Jun 23.
Bioorg Med Chem Lett. 2022.
PMID: 35752380
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The Inhibition of the Membrane-Bound Transcription Factor Site-1 Protease (MBTP1) Alleviates the p.Phe508del-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Defects in Cystic Fibrosis Cells.
Santinelli R, Benz N, Guellec J, Quinquis F, Kocas E, Thomas J, Montier T, Ka C, Luczka-Majérus E, Sage E, Férec C, Coraux C, Trouvé P.
Santinelli R, et al. Among authors: guellec j.
Cells. 2024 Jan 18;13(2):185. doi: 10.3390/cells13020185.
Cells. 2024.
PMID: 38247876
Free PMC article.
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