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Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1.
Moine E, Dimier-Poisson I, Enguehard-Gueiffier C, Logé C, Pénichon M, Moiré N, Delehouzé C, Foll-Josselin B, Ruchaud S, Bach S, Gueiffier A, Debierre-Grockiego F, Denevault-Sabourin C. Moine E, et al. Among authors: gueiffier a. Eur J Med Chem. 2015 Nov 13;105:80-105. doi: 10.1016/j.ejmech.2015.10.004. Epub 2015 Oct 9. Eur J Med Chem. 2015. PMID: 26479029
Synthesis of imidazo[1,2-a]pyridines as antiviral agents.
Gueiffier A, Mavel S, Lhassani M, Elhakmaoui A, Snoeck R, Andrei G, Chavignon O, Teulade JC, Witvrouw M, Balzarini J, De Clercq E, Chapat JP. Gueiffier A, et al. J Med Chem. 1998 Dec 3;41(25):5108-12. doi: 10.1021/jm981051y. J Med Chem. 1998. PMID: 9836626
2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist.
Enguehard-Gueiffier C, Hübner H, El Hakmaoui A, Allouchi H, Gmeiner P, Argiolas A, Melis MR, Gueiffier A. Enguehard-Gueiffier C, et al. Among authors: gueiffier a. J Med Chem. 2006 Jun 29;49(13):3938-47. doi: 10.1021/jm060166w. J Med Chem. 2006. PMID: 16789750
46 results