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Lipid-Associated Macrophages Are Induced by Cancer-Associated Fibroblasts and Mediate Immune Suppression in Breast Cancer.
Timperi E, Gueguen P, Molgora M, Magagna I, Kieffer Y, Lopez-Lastra S, Sirven P, Baudrin LG, Baulande S, Nicolas A, Champenois G, Meseure D, Vincent-Salomon A, Tardivon A, Laas E, Soumelis V, Colonna M, Mechta-Grigoriou F, Amigorena S, Romano E. Timperi E, et al. Among authors: gueguen p. Cancer Res. 2022 Sep 16;82(18):3291-3306. doi: 10.1158/0008-5472.CAN-22-1427. Cancer Res. 2022. PMID: 35862581
High prevalence of Bardet-Biedl syndrome in La Réunion Island is due to a founder variant in ARL6/BBS3.
Gouronc A, Zilliox V, Jacquemont ML, Darcel F, Leuvrey AS, Nourisson E, Antin M, Alessandri JL, Doray B, Gueguen P, Payet F, Randrianaivo H, Stoetzel C, Scheidecker S, Flodrops H, Dollfus H, Muller J. Gouronc A, et al. Among authors: gueguen p. Clin Genet. 2020 Aug;98(2):166-171. doi: 10.1111/cge.13768. Epub 2020 Jun 22. Clin Genet. 2020. PMID: 32361989
The epigenetic control of stemness in CD8+ T cell fate commitment.
Pace L, Goudot C, Zueva E, Gueguen P, Burgdorf N, Waterfall JJ, Quivy JP, Almouzni G, Amigorena S. Pace L, et al. Among authors: gueguen p. Science. 2018 Jan 12;359(6372):177-186. doi: 10.1126/science.aah6499. Science. 2018. PMID: 29326266
Splicing Patterns in SF3B1-Mutated Uveal Melanoma Generate Shared Immunogenic Tumor-Specific Neoepitopes.
Bigot J, Lalanne AI, Lucibello F, Gueguen P, Houy A, Dayot S, Ganier O, Gilet J, Tosello J, Nemati F, Pierron G, Waterfall JJ, Barnhill R, Gardrat S, Piperno-Neumann S, Popova T, Masson V, Loew D, Mariani P, Cassoux N, Amigorena S, Rodrigues M, Alsafadi S, Stern MH, Lantz O. Bigot J, et al. Among authors: gueguen p. Cancer Discov. 2021 Aug;11(8):1938-1951. doi: 10.1158/2159-8290.CD-20-0555. Epub 2021 Apr 2. Cancer Discov. 2021. PMID: 33811047
Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome.
Tkach M, Thalmensi J, Timperi E, Gueguen P, Névo N, Grisard E, Sirven P, Cocozza F, Gouronnec A, Martin-Jaular L, Jouve M, Delisle F, Manel N, Rookhuizen DC, Guerin CL, Soumelis V, Romano E, Segura E, Théry C. Tkach M, et al. Among authors: gueguen p. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2107394119. doi: 10.1073/pnas.2107394119. Epub 2022 Apr 19. Proc Natl Acad Sci U S A. 2022. PMID: 35439048 Free PMC article.
CD8+T cell responsiveness to anti-PD-1 is epigenetically regulated by Suv39h1 in melanomas.
Niborski LL, Gueguen P, Ye M, Thiolat A, Ramos RN, Caudana P, Denizeau J, Colombeau L, Rodriguez R, Goudot C, Luccarini JM, Soudé A, Bournique B, Broqua P, Pace L, Baulande S, Sedlik C, Quivy JP, Almouzni G, Cohen JL, Zueva E, Waterfall JJ, Amigorena S, Piaggio E. Niborski LL, et al. Among authors: gueguen p. Nat Commun. 2022 Jun 29;13(1):3739. doi: 10.1038/s41467-022-31504-z. Nat Commun. 2022. PMID: 35768432 Free PMC article.
74 results