Gucwa K - Search Results

1

Lactoferricin B Combined with Antibiotics Exhibits Leukemic Selectivity and Antimicrobial Activity.

Lica JJ, Gucwa K, Heldt M, Stupak A, Maciejewska N, Ptaszyńska N, Łęgowska A, Pradhan B, Gitlin-Domagalska A, Dębowski D, Jakóbkiewicz-Banecka J, Rolka K. Lica JJ, et al. Among authors: gucwa k. Molecules. 2024 Feb 1;29(3):678. doi: 10.3390/molecules29030678. Molecules. 2024. PMID: 38338422 Free PMC article.

2

Lethal perturbation of an Escherichia coli regulatory network is triggered by a restriction-modification system's regulator and can be mitigated by excision of the cryptic prophage Rac.

Gucwa K, Wons E, Wisniewska A, Jakalski M, Dubiak Z, Kozlowski LP, Mruk I. Gucwa K, et al. Nucleic Acids Res. 2024 Apr 12;52(6):2942-2960. doi: 10.1093/nar/gkad1234. Nucleic Acids Res. 2024. PMID: 38153127 Free PMC article.

3

Dual-Activity Fluoroquinolone-Transportan 10 Conjugates Offer Alternative Leukemia Therapy during Hematopoietic Cell Transplantation.

Lica JJ, Heldt M, Wieczór M, Chodnicki P, Ptaszyńska N, Maciejewska N, Łęgowska A, Brankiewicz W, Gucwa K, Stupak A, Pradhan B, Gitlin-Domagalska A, Dębowski D, Milewski S, Bieniaszewska M, Grabe GJ, Hellmann A, Rolka K. Lica JJ, et al. Among authors: gucwa k. Mol Pharmacol. 2023 Dec 15;105(1):39-53. doi: 10.1124/molpharm.123.000735. Mol Pharmacol. 2023. PMID: 37977824

4

Molecular basis for lethal cross-talk between two unrelated bacterial transcription factors - the regulatory protein of a restriction-modification system and the repressor of a defective prophage.

Wisniewska A, Wons E, Potrykus K, Hinrichs R, Gucwa K, Graumann PL, Mruk I. Wisniewska A, et al. Among authors: gucwa k. Nucleic Acids Res. 2022 Oct 28;50(19):10964-10980. doi: 10.1093/nar/gkac914. Nucleic Acids Res. 2022. PMID: 36271797 Free PMC article.

5

Effective Drug Concentration and Selectivity Depends on Fraction of Primitive Cells.

Lica JJ, Wieczór M, Grabe GJ, Heldt M, Jancz M, Misiak M, Gucwa K, Brankiewicz W, Maciejewska N, Stupak A, Bagiński M, Rolka K, Hellmann A, Składanowski A. Lica JJ, et al. Among authors: gucwa k. Int J Mol Sci. 2021 May 6;22(9):4931. doi: 10.3390/ijms22094931. Int J Mol Sci. 2021. PMID: 34066491 Free PMC article.

6

Conjugates of Ciprofloxacin and Levofloxacin with Cell-Penetrating Peptide Exhibit Antifungal Activity and Mammalian Cytotoxicity.

Ptaszyńska N, Gucwa K, Olkiewicz K, Heldt M, Serocki M, Stupak A, Martynow D, Dębowski D, Gitlin-Domagalska A, Lica J, Łęgowska A, Milewski S, Rolka K. Ptaszyńska N, et al. Among authors: gucwa k. Int J Mol Sci. 2020 Jun 30;21(13):4696. doi: 10.3390/ijms21134696. Int J Mol Sci. 2020. PMID: 32630159 Free PMC article.

7

Truncation of Huia versabilis Bowman-Birk inhibitor increases its selectivity, matriptase-1 inhibitory activity and proteolytic stability.

Gitlin-Domagalska A, Dębowski D, Gucwa K, Starego D, Ptaszyńska N, Sieradzan A, Karczyńska A, Samsonov SA, Mangold M, Gütschow M, Łęgowska A, Rolka K. Gitlin-Domagalska A, et al. Among authors: gucwa k. Biochimie. 2020 Apr-May;171-172:178-186. doi: 10.1016/j.biochi.2020.03.006. Epub 2020 Mar 10. Biochimie. 2020. PMID: 32169666

8

Peptide dendrimers as antifungal agents and carriers for potential antifungal agent-N³ -(4-methoxyfumaroyl)-(S)-2,3-diaminopropanoic acid-synthesis and antimicrobial activity.

Stolarska M, Gucwa K, Urbańczyk-Lipkowska Z, Andruszkiewicz R. Stolarska M, et al. Among authors: gucwa k. J Pept Sci. 2020 Jan;26(1):e3226. doi: 10.1002/psc.3226. Epub 2019 Dec 16. J Pept Sci. 2020. PMID: 31845463

9

Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities.

Ptaszyńska N, Gucwa K, Olkiewicz K, Łȩgowska A, Okońska J, Ruczyński J, Gitlin-Domagalska A, Dȩbowski D, Milewski S, Rolka K. Ptaszyńska N, et al. Among authors: gucwa k. ACS Chem Biol. 2019 Oct 18;14(10):2233-2242. doi: 10.1021/acschembio.9b00538. Epub 2019 Sep 25. ACS Chem Biol. 2019. PMID: 31513374

10

Peptide conjugates of lactoferricin analogues and antimicrobials-Design, chemical synthesis, and evaluation of antimicrobial activity and mammalian cytotoxicity.

Ptaszyńska N, Olkiewicz K, Okońska J, Gucwa K, Łęgowska A, Gitlin-Domagalska A, Dębowski D, Lica J, Heldt M, Milewski S, Ng TB, Rolka K. Ptaszyńska N, et al. Among authors: gucwa k. Peptides. 2019 Jul;117:170079. doi: 10.1016/j.peptides.2019.04.006. Epub 2019 Apr 5. Peptides. 2019. PMID: 30959143

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