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Development of a PET Tracer for OGA with Improved Kinetics in the Living Brain.
Cook BE, Nag S, Arakawa R, Lin EY, Stratman N, Guckian K, Hering H, Lulla M, Choi J, Salinas C, Genung NE, Morén AF, Bolin M, Boscutti G, Plisson C, Martarello L, Halldin C, Kaliszczak MA. Cook BE, et al. Among authors: guckian k. J Nucl Med. 2023 Oct;64(10):1588-1593. doi: 10.2967/jnumed.122.265225. Epub 2023 Jul 6. J Nucl Med. 2023. PMID: 37934021
Development of a Novel [11C]CO-Labeled Positron Emission Tomography Radioligand [11C]BIO-1819578 for the Detection of O-GlcNAcase Enzyme Activity.
Nag S, Bolin M, Datta P, Arakawa R, Forsberg Morén A, Khani Maynaq Y, Lin E, Genung N, Hering H, Guckian K, Martarello L, Kaliszczak M, Halldin C. Nag S, et al. Among authors: guckian k. ACS Chem Neurosci. 2023 Jul 19;14(14):2560-2568. doi: 10.1021/acschemneuro.3c00247. Epub 2023 Jun 28. ACS Chem Neurosci. 2023. PMID: 37377046 Free PMC article.
Novel Potent Selective Orally Active S1P5 Receptor Antagonists.
Ma B, Guckian KM, Liu XG, Yang C, Li B, Scannevin R, Mingueneau M, Drouillard A, Walzer T. Ma B, et al. Among authors: guckian km. ACS Med Chem Lett. 2021 Jan 15;12(3):351-355. doi: 10.1021/acsmedchemlett.0c00631. eCollection 2021 Mar 11. ACS Med Chem Lett. 2021. PMID: 33738061 Free PMC article.
Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction.
Lin EYS, Silvian LF, Marcotte DJ, Banos CC, Jow F, Chan TR, Arduini RM, Qian F, Baker DP, Bergeron C, Hession CA, Huganir RL, Borenstein CF, Enyedy I, Zou J, Rohde E, Wittmann M, Kumaravel G, Rhodes KJ, Scannevin RH, Dunah AW, Guckian KM. Lin EYS, et al. Among authors: guckian km. Sci Rep. 2018 Sep 7;8(1):13438. doi: 10.1038/s41598-018-31680-3. Sci Rep. 2018. PMID: 30194389 Free PMC article.
28 results