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Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib.
Steeghs N, Mathijssen RH, Wessels JA, de Graan AJ, van der Straaten T, Mariani M, Laffranchi B, Comis S, de Jonge MJ, Gelderblom H, Guchelaar HJ. Steeghs N, et al. Among authors: guchelaar hj. Invest New Drugs. 2011 Oct;29(5):953-62. doi: 10.1007/s10637-010-9405-7. Epub 2010 Feb 25. Invest New Drugs. 2011. PMID: 20182906 Free PMC article. Clinical Trial.
Efficacy and toxicity of methotrexate in early rheumatoid arthritis are associated with single-nucleotide polymorphisms in genes coding for folate pathway enzymes.
Wessels JA, de Vries-Bouwstra JK, Heijmans BT, Slagboom PE, Goekoop-Ruiterman YP, Allaart CF, Kerstens PJ, van Zeben D, Breedveld FC, Dijkmans BA, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Apr;54(4):1087-95. doi: 10.1002/art.21726. Arthritis Rheum. 2006. PMID: 16572443 Free article.
Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritis.
Wessels JA, Kooloos WM, De Jonge R, De Vries-Bouwstra JK, Allaart CF, Linssen A, Collee G, De Sonnaville P, Lindemans J, Huizinga TW, Guchelaar HJ. Wessels JA, et al. Among authors: guchelaar hj. Arthritis Rheum. 2006 Sep;54(9):2830-9. doi: 10.1002/art.22032. Arthritis Rheum. 2006. PMID: 16947783 Free article. Clinical Trial.
Genetic markers of treatment response in rheumatoid arthritis.
Wesoly J, Wessels JA, Guchelaar HJ, Huizinga TW. Wesoly J, et al. Among authors: guchelaar hj. Curr Rheumatol Rep. 2006 Oct;8(5):369-77. doi: 10.1007/s11926-006-0068-5. Curr Rheumatol Rep. 2006. PMID: 16973111 Review.
Exploratory analysis of four polymorphisms in human GGH and FPGS genes and their effect in methotrexate-treated rheumatoid arthritis patients.
van der Straaten RJ, Wessels JA, de Vries-Bouwstra JK, Goekoop-Ruiterman YP, Allaart CF, Bogaartz J, Tiller M, Huizinga TW, Guchelaar HJ. van der Straaten RJ, et al. Among authors: guchelaar hj. Pharmacogenomics. 2007 Feb;8(2):141-50. doi: 10.2217/14622416.8.2.141. Pharmacogenomics. 2007. PMID: 17286537 Clinical Trial.
Is rectal administration an alternative route for imatinib?
van Erp NP, Oostendorp RL, Guchelaar HJ, Schellens JH, Gelderblom H. van Erp NP, et al. Among authors: guchelaar hj. Cancer Chemother Pharmacol. 2007 Sep;60(4):623-4. doi: 10.1007/s00280-006-0409-0. Epub 2007 Feb 8. Cancer Chemother Pharmacol. 2007. PMID: 17287936 Free article. No abstract available.
460 results