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The dynamics of an immunotherapy duo.
Shavkunov AS, Gubin MM. Shavkunov AS, et al. Among authors: gubin mm. Nat Cancer. 2022 Apr;3(4):376-378. doi: 10.1038/s43018-022-00362-5. Nat Cancer. 2022. PMID: 35484417 No abstract available.
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.
Gubin MM, Zhang X, Schuster H, Caron E, Ward JP, Noguchi T, Ivanova Y, Hundal J, Arthur CD, Krebber WJ, Mulder GE, Toebes M, Vesely MD, Lam SS, Korman AJ, Allison JP, Freeman GJ, Sharpe AH, Pearce EL, Schumacher TN, Aebersold R, Rammensee HG, Melief CJ, Mardis ER, Gillanders WE, Artyomov MN, Schreiber RD. Gubin MM, et al. Nature. 2014 Nov 27;515(7528):577-81. doi: 10.1038/nature13988. Nature. 2014. PMID: 25428507 Free PMC article.
MHC-II neoantigens shape tumour immunity and response to immunotherapy.
Alspach E, Lussier DM, Miceli AP, Kizhvatov I, DuPage M, Luoma AM, Meng W, Lichti CF, Esaulova E, Vomund AN, Runci D, Ward JP, Gubin MM, Medrano RFV, Arthur CD, White JM, Sheehan KCF, Chen A, Wucherpfennig KW, Jacks T, Unanue ER, Artyomov MN, Schreiber RD. Alspach E, et al. Among authors: gubin mm. Nature. 2019 Oct;574(7780):696-701. doi: 10.1038/s41586-019-1671-8. Epub 2019 Oct 23. Nature. 2019. PMID: 31645760 Free PMC article.
TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy.
Molgora M, Esaulova E, Vermi W, Hou J, Chen Y, Luo J, Brioschi S, Bugatti M, Omodei AS, Ricci B, Fronick C, Panda SK, Takeuchi Y, Gubin MM, Faccio R, Cella M, Gilfillan S, Unanue ER, Artyomov MN, Schreiber RD, Colonna M. Molgora M, et al. Among authors: gubin mm. Cell. 2020 Aug 20;182(4):886-900.e17. doi: 10.1016/j.cell.2020.07.013. Epub 2020 Aug 11. Cell. 2020. PMID: 32783918 Free PMC article.
BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.
Salmon AJ, Shavkunov AS, Miao Q, Jarjour NN, Keshari S, Esaulova E, Williams CD, Ward JP, Highsmith AM, Pineda JE, Taneja R, Chen K, Edelson BT, Gubin MM. Salmon AJ, et al. Among authors: gubin mm. Cancer Immunol Res. 2022 May 3;10(5):597-611. doi: 10.1158/2326-6066.CIR-21-0129. Cancer Immunol Res. 2022. PMID: 35181783 Free PMC article.
Cancer Immunoediting in the Era of Immuno-oncology.
Gubin MM, Vesely MD. Gubin MM, et al. Clin Cancer Res. 2022 Sep 15;28(18):3917-3928. doi: 10.1158/1078-0432.CCR-21-1804. Clin Cancer Res. 2022. PMID: 35594163 Free PMC article.
Neoantigen Cancer Vaccines and Different Immune Checkpoint Therapies Each Utilize Both Converging and Distinct Mechanisms that in Combination Enable Synergistic Therapeutic Efficacy.
Keshari S, Shavkunov AS, Miao Q, Saha A, Williams CD, Highsmith AM, Pineda JE, Alspach E, Hu KH, Pauken KE, Chen K, Gubin MM. Keshari S, et al. Among authors: gubin mm. bioRxiv [Preprint]. 2024 Jan 26:2023.12.20.570816. doi: 10.1101/2023.12.20.570816. bioRxiv. 2024. PMID: 38187708 Free PMC article. Preprint.
Intestinal toxicity to CTLA-4 blockade driven by IL-6 and myeloid infiltration.
Zhou Y, Medik YB, Patel B, Zamler DB, Chen S, Chapman T, Schneider S, Park EM, Babcock RL, Chrisikos TT, Kahn LM, Dyevoich AM, Pineda JE, Wong MC, Mishra AK, Cass SH, Cogdill AP, Johnson DH, Johnson SB, Wani K, Ledesma DA, Hudgens CW, Wang J, Wadud Khan MA, Peterson CB, Joon AY, Peng W, Li HS, Arora R, Tang X, Raso MG, Zhang X, Foo WC, Tetzlaff MT, Diehl GE, Clise-Dwyer K, Whitley EM, Gubin MM, Allison JP, Hwu P, Ajami NJ, Diab A, Wargo JA, Watowich SS. Zhou Y, et al. Among authors: gubin mm. J Exp Med. 2023 Feb 6;220(2):e20221333. doi: 10.1084/jem.20221333. Epub 2022 Nov 11. J Exp Med. 2023. PMID: 36367776 Free PMC article.
CANCER. The odds of immunotherapy success.
Gubin MM, Schreiber RD. Gubin MM, et al. Science. 2015 Oct 9;350(6257):158-9. doi: 10.1126/science.aad4140. Science. 2015. PMID: 26450194 No abstract available.
31 results