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AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation.
Asteriti IA, Polverino F, Stagni V, Sterbini V, Ascanelli C, Naso FD, Mastrangelo A, Rosa A, Paiardini A, Lindon C, Guarguaglini G. Asteriti IA, et al. Among authors: guarguaglini g. Life Sci Alliance. 2023 Feb 16;6(5):e202201726. doi: 10.26508/lsa.202201726. Print 2023 May. Life Sci Alliance. 2023. PMID: 36797043 Free PMC article.
The Aurora-A/TPX2 complex: a novel oncogenic holoenzyme?
Asteriti IA, Rensen WM, Lindon C, Lavia P, Guarguaglini G. Asteriti IA, et al. Among authors: guarguaglini g. Biochim Biophys Acta. 2010 Dec;1806(2):230-9. doi: 10.1016/j.bbcan.2010.08.001. Epub 2010 Aug 12. Biochim Biophys Acta. 2010. PMID: 20708655 Review.
Control of Aurora-A stability through interaction with TPX2.
Giubettini M, Asteriti IA, Scrofani J, De Luca M, Lindon C, Lavia P, Guarguaglini G. Giubettini M, et al. Among authors: guarguaglini g. J Cell Sci. 2011 Jan 1;124(Pt 1):113-22. doi: 10.1242/jcs.075457. Epub 2010 Dec 8. J Cell Sci. 2011. PMID: 21147853 Free PMC article.
NuMA Phosphorylation by Aurora-A Orchestrates Spindle Orientation.
Gallini S, Carminati M, De Mattia F, Pirovano L, Martini E, Oldani A, Asteriti IA, Guarguaglini G, Mapelli M. Gallini S, et al. Among authors: guarguaglini g. Curr Biol. 2016 Feb 22;26(4):458-69. doi: 10.1016/j.cub.2015.12.051. Epub 2016 Jan 28. Curr Biol. 2016. PMID: 26832443 Free article.
Identification of small molecule inhibitors of the Aurora-A/TPX2 complex.
Asteriti IA, Daidone F, Colotti G, Rinaldo S, Lavia P, Guarguaglini G, Paiardini A. Asteriti IA, et al. Among authors: guarguaglini g. Oncotarget. 2017 May 9;8(19):32117-32133. doi: 10.18632/oncotarget.16738. Oncotarget. 2017. PMID: 28389630 Free PMC article.
47 results