Guan L - Search Results

1

Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport.

Chua GL, Tan BC, Loke RYJ, He M, Chin CF, Wong BH, Kuk ACY, Ding M, Wenk MR, Guan L, Torta F, Silver DL. Chua GL, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2023 Mar 7;120(10):e2215290120. doi: 10.1073/pnas.2215290120. Epub 2023 Feb 27. Proc Natl Acad Sci U S A. 2023. PMID: 36848557 Free PMC article.

2

A 3D structure model of the melibiose permease of Escherichia coli represents a distinctive fold for Na+ symporters.

Yousef MS, Guan L. Yousef MS, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2009 Sep 8;106(36):15291-6. doi: 10.1073/pnas.0905516106. Epub 2009 Aug 19. Proc Natl Acad Sci U S A. 2009. PMID: 19706416 Free PMC article.

3

Manipulating phospholipids for crystallization of a membrane transport protein.

Guan L, Smirnova IN, Verner G, Nagamori S, Kaback HR. Guan L, et al. Proc Natl Acad Sci U S A. 2006 Feb 7;103(6):1723-6. doi: 10.1073/pnas.0510922103. Epub 2006 Jan 30. Proc Natl Acad Sci U S A. 2006. PMID: 16446422 Free PMC article.

4

Structural determination of wild-type lactose permease.

Guan L, Mirza O, Verner G, Iwata S, Kaback HR. Guan L, et al. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15294-8. doi: 10.1073/pnas.0707688104. Epub 2007 Sep 19. Proc Natl Acad Sci U S A. 2007. PMID: 17881559 Free PMC article.

5

Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc.

Hariharan P, Balasubramaniam D, Peterkofsky A, Kaback HR, Guan L. Hariharan P, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2407-12. doi: 10.1073/pnas.1500891112. Epub 2015 Feb 9. Proc Natl Acad Sci U S A. 2015. PMID: 25675534 Free PMC article.

6

Structure, function, and ion-binding properties of a K⁺ channel stabilized in the 2,4-ion-bound configuration.

Tilegenova C, Cortes DM, Jahovic N, Hardy E, Hariharan P, Guan L, Cuello LG. Tilegenova C, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2019 Aug 20;116(34):16829-16834. doi: 10.1073/pnas.1901888116. Epub 2019 Aug 6. Proc Natl Acad Sci U S A. 2019. PMID: 31387976 Free PMC article.

7

X-ray crystallography reveals molecular recognition mechanism for sugar binding in a melibiose transporter MelB.

Guan L, Hariharan P. Guan L, et al. Commun Biol. 2021 Aug 2;4(1):931. doi: 10.1038/s42003-021-02462-x. Commun Biol. 2021. PMID: 34341464 Free PMC article.

8

An approach to membrane protein structure without crystals.

Sorgen PL, Hu Y, Guan L, Kaback HR, Girvin ME. Sorgen PL, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14037-40. doi: 10.1073/pnas.182552199. Epub 2002 Oct 21. Proc Natl Acad Sci U S A. 2002. PMID: 12391320 Free PMC article.

9

Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli.

Vázquez-Ibar JL, Guan L, Svrakic M, Kaback HR. Vázquez-Ibar JL, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12706-11. doi: 10.1073/pnas.1835645100. Epub 2003 Oct 17. Proc Natl Acad Sci U S A. 2003. PMID: 14566061 Free PMC article.

10

Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition.

Chaptal V, Kwon S, Sawaya MR, Guan L, Kaback HR, Abramson J. Chaptal V, et al. Among authors: guan l. Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9361-6. doi: 10.1073/pnas.1105687108. Epub 2011 May 18. Proc Natl Acad Sci U S A. 2011. PMID: 21593407 Free PMC article.

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