Guan K - Search Results

1

Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT₁-fragment domains in cardiomyocytes.

Weninger G, Pochechueva T, El Chami D, Luo X, Kohl T, Brandenburg S, Urlaub H, Guan K, Lenz C, Lehnart SE. Weninger G, et al. Among authors: guan k. Sci Rep. 2022 Jun 20;12(1):10387. doi: 10.1038/s41598-022-14320-9. Sci Rep. 2022. PMID: 35725601 Free PMC article.

2

Sensing Cardiac Electrical Activity With a Cardiac Myocyte--Targeted Optogenetic Voltage Indicator.

Chang Liao ML, de Boer TP, Mutoh H, Raad N, Richter C, Wagner E, Downie BR, Unsöld B, Arooj I, Streckfuss-Bömeke K, Döker S, Luther S, Guan K, Wagner S, Lehnart SE, Maier LS, Stühmer W, Wettwer E, van Veen T, Morlock MM, Knöpfel T, Zimmermann WH. Chang Liao ML, et al. Among authors: guan k. Circ Res. 2015 Aug 14;117(5):401-12. doi: 10.1161/CIRCRESAHA.117.306143. Epub 2015 Jun 15. Circ Res. 2015. PMID: 26078285

3

hiPSC-derived cardiomyocytes from Brugada Syndrome patients without identified mutations do not exhibit clear cellular electrophysiological abnormalities.

Veerman CC, Mengarelli I, Guan K, Stauske M, Barc J, Tan HL, Wilde AA, Verkerk AO, Bezzina CR. Veerman CC, et al. Among authors: guan k. Sci Rep. 2016 Aug 3;6:30967. doi: 10.1038/srep30967. Sci Rep. 2016. PMID: 27485484 Free PMC article.

4

Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.

Streckfuss-Bömeke K, Tiburcy M, Fomin A, Luo X, Li W, Fischer C, Özcelik C, Perrot A, Sossalla S, Haas J, Vidal RO, Rebs S, Khadjeh S, Meder B, Bonn S, Linke WA, Zimmermann WH, Hasenfuss G, Guan K. Streckfuss-Bömeke K, et al. Among authors: guan k. J Mol Cell Cardiol. 2017 Dec;113:9-21. doi: 10.1016/j.yjmcc.2017.09.008. Epub 2017 Sep 21. J Mol Cell Cardiol. 2017. PMID: 28941705 Free article.

5

Deep phenotyping of human induced pluripotent stem cell-derived atrial and ventricular cardiomyocytes.

Cyganek L, Tiburcy M, Sekeres K, Gerstenberg K, Bohnenberger H, Lenz C, Henze S, Stauske M, Salinas G, Zimmermann WH, Hasenfuss G, Guan K. Cyganek L, et al. Among authors: guan k. JCI Insight. 2018 Jun 21;3(12):e99941. doi: 10.1172/jci.insight.99941. eCollection 2018 Jun 21. JCI Insight. 2018. PMID: 29925689 Free PMC article.

6

Sarcoplasmic reticulum calcium leak contributes to arrhythmia but not to heart failure progression.

Mohamed BA, Hartmann N, Tirilomis P, Sekeres K, Li W, Neef S, Richter C, Zeisberg EM, Kattner L, Didié M, Guan K, Schmitto JD, Lehnart SE, Luther S, Voigt N, Seidler T, Sossalla S, Hasenfuss G, Toischer K. Mohamed BA, et al. Among authors: guan k. Sci Transl Med. 2018 Sep 12;10(458):eaan0724. doi: 10.1126/scitranslmed.aan0724. Sci Transl Med. 2018. PMID: 30209242

7

The reduced activity of PP-1α under redox stress condition is a consequence of GSH-mediated transient disulfide formation.

Singh S, Lämmle S, Giese H, Kämmerer S, Meyer-Roxlau S, Alfar EA, Dihazi H, Guan K, El-Armouche A, Richter F. Singh S, et al. Among authors: guan k. Sci Rep. 2018 Dec 7;8(1):17711. doi: 10.1038/s41598-018-36267-6. Sci Rep. 2018. PMID: 30531830 Free PMC article.

8

Control of p21Cip by BRCA1-associated protein is critical for cardiomyocyte cell cycle progression and survival.

Volland C, Schott P, Didié M, Männer J, Unsöld B, Toischer K, Schmidt C, Urlaub H, Nickels K, Knöll R, Schmidt A, Guan K, Hasenfuß G, Seidler T. Volland C, et al. Among authors: guan k. Cardiovasc Res. 2020 Mar 1;116(3):592-604. doi: 10.1093/cvr/cvz177. Cardiovasc Res. 2020. PMID: 31286143

9

Establishment of an automated patch-clamp platform for electrophysiological and pharmacological evaluation of hiPSC-CMs.

Li W, Luo X, Ulbricht Y, Wagner M, Piorkowski C, El-Armouche A, Guan K. Li W, et al. Among authors: guan k. Stem Cell Res. 2019 Dec;41:101662. doi: 10.1016/j.scr.2019.101662. Epub 2019 Nov 18. Stem Cell Res. 2019. PMID: 31809994 Free article.

10

Electrophysiological Abnormalities in VLCAD Deficient hiPSC-Cardiomyocytes Can Be Improved by Lowering Accumulation of Fatty Acid Oxidation Intermediates.

Knottnerus SJG, Mengarelli I, Wüst RCI, Baartscheer A, Bleeker JC, Coronel R, Ferdinandusse S, Guan K, IJlst L, Li W, Luo X, Portero VM, Ulbricht Y, Visser G, Wanders RJA, Wijburg FA, Verkerk AO, Houtkooper RH, Bezzina CR. Knottnerus SJG, et al. Among authors: guan k. Int J Mol Sci. 2020 Apr 8;21(7):2589. doi: 10.3390/ijms21072589. Int J Mol Sci. 2020. PMID: 32276429 Free PMC article.

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