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Switch From Fetal to Adult SCN5A Isoform in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Unmasks the Cellular Phenotype of a Conduction Disease-Causing Mutation.
Veerman CC, Mengarelli I, Lodder EM, Kosmidis G, Bellin M, Zhang M, Dittmann S, Guan K, Wilde AAM, Schulze-Bahr E, Greber B, Bezzina CR, Verkerk AO. Veerman CC, et al. Among authors: guan k. J Am Heart Assoc. 2017 Jul 24;6(7):e005135. doi: 10.1161/JAHA.116.005135. J Am Heart Assoc. 2017. PMID: 28739862 Free PMC article.
Catecholamine-Dependent β-Adrenergic Signaling in a Pluripotent Stem Cell Model of Takotsubo Cardiomyopathy.
Borchert T, Hübscher D, Guessoum CI, Lam TD, Ghadri JR, Schellinger IN, Tiburcy M, Liaw NY, Li Y, Haas J, Sossalla S, Huber MA, Cyganek L, Jacobshagen C, Dressel R, Raaz U, Nikolaev VO, Guan K, Thiele H, Meder B, Wollnik B, Zimmermann WH, Lüscher TF, Hasenfuss G, Templin C, Streckfuss-Bömeke K. Borchert T, et al. Among authors: guan k. J Am Coll Cardiol. 2017 Aug 22;70(8):975-991. doi: 10.1016/j.jacc.2017.06.061. J Am Coll Cardiol. 2017. PMID: 28818208 Free article.
Severe DCM phenotype of patient harboring RBM20 mutation S635A can be modeled by patient-specific induced pluripotent stem cell-derived cardiomyocytes.
Streckfuss-Bömeke K, Tiburcy M, Fomin A, Luo X, Li W, Fischer C, Özcelik C, Perrot A, Sossalla S, Haas J, Vidal RO, Rebs S, Khadjeh S, Meder B, Bonn S, Linke WA, Zimmermann WH, Hasenfuss G, Guan K. Streckfuss-Bömeke K, et al. Among authors: guan k. J Mol Cell Cardiol. 2017 Dec;113:9-21. doi: 10.1016/j.yjmcc.2017.09.008. Epub 2017 Sep 21. J Mol Cell Cardiol. 2017. PMID: 28941705 Free article.
Enhanced structural maturation of human induced pluripotent stem cell-derived cardiomyocytes under a controlled microenvironment in a microfluidic system.
Kolanowski TJ, Busek M, Schubert M, Dmitrieva A, Binnewerg B, Pöche J, Fisher K, Schmieder F, Grünzner S, Hansen S, Richter A, El-Armouche A, Sonntag F, Guan K. Kolanowski TJ, et al. Among authors: guan k. Acta Biomater. 2020 Jan 15;102:273-286. doi: 10.1016/j.actbio.2019.11.044. Epub 2019 Nov 26. Acta Biomater. 2020. PMID: 31778832
963 results