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Next-Generation Hypoxic Cell Radiosensitizers: Nitroimidazole Alkylsulfonamides.
Bonnet M, Hong CR, Wong WW, Liew LP, Shome A, Wang J, Gu Y, Stevenson RJ, Qi W, Anderson RF, Pruijn FB, Wilson WR, Jamieson SMF, Hicks KO, Hay MP. Bonnet M, et al. Among authors: gu y. J Med Chem. 2018 Feb 8;61(3):1241-1254. doi: 10.1021/acs.jmedchem.7b01678. Epub 2018 Jan 11. J Med Chem. 2018. PMID: 29253343
Hypoxic selectivity and solubility--investigating the properties of A-ring substituted nitro seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-ones (nitroCBIs) as hypoxia-activated prodrugs for antitumor therapy.
Tercel M, Yang S, Atwell GJ, Smith E, Gu Y, Anderson RF, Denny WA, Wilson WR, Pruijn FB. Tercel M, et al. Among authors: gu y. Bioorg Med Chem. 2010 Jul 15;18(14):4997-5006. doi: 10.1016/j.bmc.2010.06.001. Epub 2010 Jun 8. Bioorg Med Chem. 2010. PMID: 20580559
Novel nitroimidazole alkylsulfonamides as hypoxic cell radiosensitisers.
Bonnet M, Hong CR, Gu Y, Anderson RF, Wilson WR, Pruijn FB, Wang J, Hicks KO, Hay MP. Bonnet M, et al. Among authors: gu y. Bioorg Med Chem. 2014 Apr 1;22(7):2123-32. doi: 10.1016/j.bmc.2014.02.039. Epub 2014 Mar 3. Bioorg Med Chem. 2014. PMID: 24650701
Analysis of the hypoxia-activated dinitrobenzamide mustard phosphate pre-prodrug PR-104 and its alcohol metabolite PR-104A in plasma and tissues by liquid chromatography-mass spectrometry.
Patel K, Lewiston D, Gu Y, Hicks KO, Wilson WR. Patel K, et al. Among authors: gu y. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Sep 1;856(1-2):302-11. doi: 10.1016/j.jchromb.2007.06.035. Epub 2007 Jul 6. J Chromatogr B Analyt Technol Biomed Life Sci. 2007. PMID: 17644498
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