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Aging is associated with an expansion of CD49fhi mammary stem cells that show a decline in function and increased transformation potential.
Dong Q, Gao H, Shi Y, Zhang F, Gu X, Wu A, Wang D, Chen Y, Bandyopadhyay A, Yeh IT, Daniel BJ, Chen Y, Zou Y, Rebel VL, Walter CA, Lu J, Huang C, Sun LZ. Dong Q, et al. Among authors: gu x. Aging (Albany NY). 2016 Nov 15;8(11):2754-2776. doi: 10.18632/aging.101082. Aging (Albany NY). 2016. PMID: 27852980 Free PMC article.
Gli2 mediates the development of castration‑resistant prostate cancer.
Xia L, Bouamar H, Gu X, Zeballos C, Qin T, Wang B, Zhou Y, Wang Y, Yang J, Zhu H, Zhang W, Houghton PJ, Sun LZ. Xia L, et al. Among authors: gu x. Int J Oncol. 2020 Jul;57(1):100-112. doi: 10.3892/ijo.2020.5044. Epub 2020 Apr 13. Int J Oncol. 2020. PMID: 32319599 Free PMC article.
GLI3 Is Stabilized by SPOP Mutations and Promotes Castration Resistance via Functional Cooperation with Androgen Receptor in Prostate Cancer.
Burleson M, Deng JJ, Qin T, Duong TM, Yan Y, Gu X, Das D, Easley A, Liss MA, Yew PR, Bedolla R, Kumar AP, Huang TH, Zou Y, Chen Y, Chen CL, Huang H, Sun LZ, Boyer TG. Burleson M, et al. Among authors: gu x. Mol Cancer Res. 2022 Jan;20(1):62-76. doi: 10.1158/1541-7786.MCR-21-0108. Epub 2021 Oct 5. Mol Cancer Res. 2022. PMID: 34610962 Free PMC article.
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