Gu W - Search Results

1

Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4.

Mo Y, Duan S, Zhang X, Hua X, Zhou H, Wei HJ, Watanabe J, McQuillan N, Su Z, Gu W, Wu CC, Vakoc CR, Hashizume R, Chang K, Zhang Z. Mo Y, et al. Among authors: gu w. Cancer Discov. 2022 Dec 2;12(12):2906-2929. doi: 10.1158/2159-8290.CD-21-1492. Cancer Discov. 2022. PMID: 36305747 Free PMC article.

2

Mutant p53 on the Path to Metastasis.

Tang Q, Su Z, Gu W, Rustgi AK. Tang Q, et al. Among authors: gu w. Trends Cancer. 2020 Jan;6(1):62-73. doi: 10.1016/j.trecan.2019.11.004. Epub 2019 Dec 16. Trends Cancer. 2020. PMID: 31952783 Free PMC article. Review.

3

Mutant p53 regulates Survivin to foster lung metastasis.

Tang Q, Efe G, Chiarella AM, Leung J, Chen M, Yamazoe T, Su Z, Pitarresi JR, Li J, Islam M, Karakasheva T, Klein-Szanto AJ, Pan S, Hu J, Natsugoe S, Gu W, Stanger BZ, Wong KK, Diehl JA, Bass AJ, Nakagawa H, Murphy ME, Rustgi AK. Tang Q, et al. Among authors: gu w. Genes Dev. 2021 Apr 1;35(7-8):528-541. doi: 10.1101/gad.340505.120. Epub 2021 Mar 18. Genes Dev. 2021. PMID: 33737385 Free PMC article.

4

An unexpected role for Dicer as a reader of the unacetylated DNA binding domain of p53 in transcriptional regulation.

Yang X, Wang X, Li Z, Duan S, Li H, Jin J, Zhang Z, Gu W. Yang X, et al. Among authors: gu w. Sci Adv. 2021 Oct 29;7(44):eabi6684. doi: 10.1126/sciadv.abi6684. Epub 2021 Oct 27. Sci Adv. 2021. PMID: 34705508 Free PMC article.

5

ALOX5-mediated ferroptosis acts as a distinct cell death pathway upon oxidative stress in Huntington's disease.

Song S, Su Z, Kon N, Chu B, Li H, Jiang X, Luo J, Stockwell BR, Gu W. Song S, et al. Among authors: gu w. Genes Dev. 2023 Mar 1;37(5-6):204-217. doi: 10.1101/gad.350211.122. Epub 2023 Mar 15. Genes Dev. 2023. PMID: 36921996 Free PMC article.

6

Specific regulation of BACH1 by the hotspot mutant p53^R175H reveals a distinct gain-of-function mechanism.

Su Z, Kon N, Yi J, Zhao H, Zhang W, Tang Q, Li H, Kobayashi H, Li Z, Duan S, Liu Y, Olive KP, Zhang Z, Honig B, Manfredi JJ, Rustgi AK, Gu W. Su Z, et al. Among authors: gu w. Nat Cancer. 2023 Apr;4(4):564-581. doi: 10.1038/s43018-023-00532-z. Epub 2023 Mar 27. Nat Cancer. 2023. PMID: 36973430 Free PMC article.

7

Regulation of VKORC1L1 is critical for p53-mediated tumor suppression through vitamin K metabolism.

Yang X, Wang Z, Zandkarimi F, Liu Y, Duan S, Li Z, Kon N, Zhang Z, Jiang X, Stockwell BR, Gu W. Yang X, et al. Among authors: gu w. Cell Metab. 2023 Aug 8;35(8):1474-1490.e8. doi: 10.1016/j.cmet.2023.06.014. Epub 2023 Jul 18. Cell Metab. 2023. PMID: 37467745

8

Protocol of CRISPR-Cas9 knockout screens for identifying ferroptosis regulators.

Yang X, Duan S, Li Z, Wang Z, Kon N, Zhang Z, Gu W. Yang X, et al. Among authors: gu w. STAR Protoc. 2023 Dec 15;4(4):102762. doi: 10.1016/j.xpro.2023.102762. Epub 2023 Dec 3. STAR Protoc. 2023. PMID: 38048220 Free PMC article.

9

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.

Yang X, Wang Z, Samovich SN, Kapralov AA, Amoscato AA, Tyurin VA, Dar HH, Li Z, Duan S, Kon N, Chen D, Tycko B, Zhang Z, Jiang X, Bayir H, Stockwell BR, Kagan VE, Gu W. Yang X, et al. Among authors: gu w. Cell Metab. 2024 Apr 2;36(4):762-777.e9. doi: 10.1016/j.cmet.2024.01.006. Epub 2024 Feb 2. Cell Metab. 2024. PMID: 38309267

10

GAS41 modulates ferroptosis by anchoring NRF2 on chromatin.

Wang Z, Yang X, Chen D, Liu Y, Li Z, Duan S, Zhang Z, Jiang X, Stockwell BR, Gu W. Wang Z, et al. Among authors: gu w. Nat Commun. 2024 Mar 21;15(1):2531. doi: 10.1038/s41467-024-46857-w. Nat Commun. 2024. PMID: 38514704 Free PMC article.

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