Grzyb K - Search Results

1

Single-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway.

Uriarte Huarte O, Kyriakis D, Heurtaux T, Pires-Afonso Y, Grzyb K, Halder R, Buttini M, Skupin A, Mittelbronn M, Michelucci A. Uriarte Huarte O, et al. Among authors: grzyb k. Front Immunol. 2021 Mar 29;12:639613. doi: 10.3389/fimmu.2021.639613. eCollection 2021. Front Immunol. 2021. PMID: 33854507 Free PMC article.

2

CaSiAn: a Calcium Signaling Analyzer tool.

Moein M, Grzyb K, Gonçalves Martins T, Komoto S, Peri F, Crawford AD, Fouquier d'Herouel A, Skupin A. Moein M, et al. Among authors: grzyb k. Bioinformatics. 2018 Sep 1;34(17):3052-3054. doi: 10.1093/bioinformatics/bty281. Bioinformatics. 2018. PMID: 29668830 Free PMC article.

3

New insights into the early mechanisms of epileptogenesis in a zebrafish model of Dravet syndrome.

Tiraboschi E, Martina S, van der Ent W, Grzyb K, Gawel K, Cordero-Maldonado ML, Poovathingal SK, Heintz S, Satheesh SV, Brattespe J, Xu J, Suster M, Skupin A, Esguerra CV. Tiraboschi E, et al. Among authors: grzyb k. Epilepsia. 2020 Mar;61(3):549-560. doi: 10.1111/epi.16456. Epub 2020 Feb 24. Epilepsia. 2020. PMID: 32096222

4

Single-cell transcriptomics reveals multiple neuronal cell types in human midbrain-specific organoids.

Smits LM, Magni S, Kinugawa K, Grzyb K, Luginbühl J, Sabate-Soler S, Bolognin S, Shin JW, Mori E, Skupin A, Schwamborn JC. Smits LM, et al. Among authors: grzyb k. Cell Tissue Res. 2020 Dec;382(3):463-476. doi: 10.1007/s00441-020-03249-y. Epub 2020 Jul 31. Cell Tissue Res. 2020. PMID: 32737576 Free PMC article.

5

Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology.

Golebiewska A, Hau AC, Oudin A, Stieber D, Yabo YA, Baus V, Barthelemy V, Klein E, Bougnaud S, Keunen O, Wantz M, Michelucci A, Neirinckx V, Muller A, Kaoma T, Nazarov PV, Azuaje F, De Falco A, Flies B, Richart L, Poovathingal S, Arns T, Grzyb K, Mock A, Herold-Mende C, Steino A, Brown D, May P, Miletic H, Malta TM, Noushmehr H, Kwon YJ, Jahn W, Klink B, Tanner G, Stead LF, Mittelbronn M, Skupin A, Hertel F, Bjerkvig R, Niclou SP. Golebiewska A, et al. Among authors: grzyb k. Acta Neuropathol. 2020 Dec;140(6):919-949. doi: 10.1007/s00401-020-02226-7. Epub 2020 Oct 3. Acta Neuropathol. 2020. PMID: 33009951 Free PMC article.

6

Single-nuclei chromatin profiling of ventral midbrain reveals cell identity transcription factors and cell-type-specific gene regulatory variation.

Gui Y, Grzyb K, Thomas MH, Ohnmacht J, Garcia P, Buttini M, Skupin A, Sauter T, Sinkkonen L. Gui Y, et al. Among authors: grzyb k. Epigenetics Chromatin. 2021 Sep 9;14(1):43. doi: 10.1186/s13072-021-00418-3. Epigenetics Chromatin. 2021. PMID: 34503558 Free PMC article.

7

The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1.

Walter J, Bolognin S, Poovathingal SK, Magni S, Gérard D, Antony PMA, Nickels SL, Salamanca L, Berger E, Smits LM, Grzyb K, Perfeito R, Hoel F, Qing X, Ohnmacht J, Bertacchi M, Jarazo J, Ignac T, Monzel AS, Gonzalez-Cano L, Krüger R, Sauter T, Studer M, de Almeida LP, Tronstad KJ, Sinkkonen L, Skupin A, Schwamborn JC. Walter J, et al. Among authors: grzyb k. Cell Rep. 2021 Oct 19;37(3):109864. doi: 10.1016/j.celrep.2021.109864. Cell Rep. 2021. PMID: 34686322 Free article.

8

Single-cell transcriptomics of human iPSC differentiation dynamics reveal a core molecular network of Parkinson's disease.

Novak G, Kyriakis D, Grzyb K, Bernini M, Rodius S, Dittmar G, Finkbeiner S, Skupin A. Novak G, et al. Among authors: grzyb k. Commun Biol. 2022 Jan 13;5(1):49. doi: 10.1038/s42003-021-02973-7. Commun Biol. 2022. PMID: 35027645 Free PMC article.

9

Midbrain organoids mimic early embryonic neurodevelopment and recapitulate LRRK2-p.Gly2019Ser-associated gene expression.

Zagare A, Barmpa K, Smajic S, Smits LM, Grzyb K, Grünewald A, Skupin A, Nickels SL, Schwamborn JC. Zagare A, et al. Among authors: grzyb k. Am J Hum Genet. 2022 Feb 3;109(2):311-327. doi: 10.1016/j.ajhg.2021.12.009. Epub 2022 Jan 24. Am J Hum Genet. 2022. PMID: 35077669 Free PMC article.

10

Stress hormone signalling inhibits Th1 polarization in a CD4 T-cell-intrinsic manner via mTORC1 and the circadian gene PER1.

Capelle CM, Chen A, Zeng N, Baron A, Grzyb K, Arns T, Skupin A, Ollert M, Hefeng FQ. Capelle CM, et al. Among authors: grzyb k. Immunology. 2022 Apr;165(4):428-444. doi: 10.1111/imm.13448. Epub 2022 Mar 2. Immunology. 2022. PMID: 35143696 Free PMC article.

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