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Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease.
Zaręba P, Łątka K, Mazur G, Gryzło B, Pasieka A, Godyń J, Panek D, Skrzypczak-Wiercioch A, Höfner GC, Latacz G, Maj M, Espargaró A, Sabaté R, Jóźwiak K, Wanner KT, Sałat K, Malawska B, Kulig K, Bajda M. Zaręba P, et al. Among authors: gryzlo b. Eur J Med Chem. 2023 Dec 5;261:115832. doi: 10.1016/j.ejmech.2023.115832. Epub 2023 Oct 7. Eur J Med Chem. 2023. PMID: 37837674 Free article.
Novel mouse GABA uptake inhibitors with enhanced inhibitory activity toward mGAT3/4 and their effect on pain threshold in mice.
Zaręba P, Gryzło B, Malawska K, Sałat K, Höfner GC, Nowaczyk A, Fijałkowski Ł, Rapacz A, Podkowa A, Furgała A, Żmudzki P, Wanner KT, Malawska B, Kulig K. Zaręba P, et al. Among authors: gryzlo b. Eur J Med Chem. 2020 Feb 15;188:111920. doi: 10.1016/j.ejmech.2019.111920. Epub 2019 Dec 29. Eur J Med Chem. 2020. PMID: 31901745
Experimental Drugs for Neuropathic Pain.
Salat K, Gryzlo B, Kulig K. Salat K, et al. Among authors: gryzlo b. Curr Neuropharmacol. 2018;16(8):1193-1209. doi: 10.2174/1570159X16666180510151241. Curr Neuropharmacol. 2018. PMID: 29745335 Free PMC article. Review.
Serotonin 5-HT6 Receptor Ligands and Butyrylcholinesterase Inhibitors Displaying Antioxidant Activity-Design, Synthesis and Biological Evaluation of Multifunctional Agents against Alzheimer's Disease.
Więckowski K, Szałaj N, Gryzło B, Wichur T, Góral I, Sługocka E, Sniecikowska J, Latacz G, Siwek A, Godyń J, Bucki A, Kołaczkowski M, Więckowska A. Więckowski K, et al. Among authors: gryzlo b. Int J Mol Sci. 2022 Aug 21;23(16):9443. doi: 10.3390/ijms23169443. Int J Mol Sci. 2022. PMID: 36012707 Free PMC article.
New investigational drugs for the treatment of neuropathic pain.
Sałat K, Kowalczyk P, Gryzło B, Jakubowska A, Kulig K. Sałat K, et al. Among authors: gryzlo b. Expert Opin Investig Drugs. 2014 Aug;23(8):1093-104. doi: 10.1517/13543784.2014.916688. Epub 2014 Jun 4. Expert Opin Investig Drugs. 2014. PMID: 24896842 Review.
15 results