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Human Bone Marrow Organoids for Disease Modeling, Discovery, and Validation of Therapeutic Targets in Hematologic Malignancies.
Khan AO, Rodriguez-Romera A, Reyat JS, Olijnik AA, Colombo M, Wang G, Wen WX, Sousos N, Murphy LC, Grygielska B, Perrella G, Mahony CB, Ling RE, Elliott NE, Karali CS, Stone AP, Kemble S, Cutler EA, Fielding AK, Croft AP, Bassett D, Poologasundarampillai G, Roy A, Gooding S, Rayes J, Machlus KR, Psaila B. Khan AO, et al. Among authors: grygielska b. Cancer Discov. 2023 Feb 6;13(2):364-385. doi: 10.1158/2159-8290.CD-22-0199. Cancer Discov. 2023. PMID: 36351055 Free PMC article.
Modelling the pathology and treatment of cardiac fibrosis in vascularised atrial and ventricular cardiac microtissues.
Reyat JS, di Maio A, Grygielska B, Pike J, Kemble S, Rodriguez-Romero A, Simoglou Karali C, Croft AP, Psaila B, Simões F, Rayes J, Khan AO. Reyat JS, et al. Among authors: grygielska b. Front Cardiovasc Med. 2023 Sep 1;10:1156759. doi: 10.3389/fcvm.2023.1156759. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37727305 Free PMC article.
Hydroxychloroquine inhibits hemolysis-induced arterial thrombosis ex vivo and improves lung perfusion in hemin-treated mice.
Bourne JH, Perrella G, El-Awaisi J, Terry LV, Tinkova V, Hogg RL, Gant P, Grygielska B, Kalia N, Kavanagh D, Brill A, Dimitrov JD, Watson SP, Rayes J. Bourne JH, et al. Among authors: grygielska b. J Thromb Haemost. 2024 Apr 24:S1538-7836(24)00226-5. doi: 10.1016/j.jtha.2024.04.008. Online ahead of print. J Thromb Haemost. 2024. PMID: 38670315 Free article.
Platelet CLEC-2 protects against lung injury via effects of its ligand podoplanin on inflammatory alveolar macrophages in the mouse.
Lax S, Rayes J, Wichaiyo S, Haining EJ, Lowe K, Grygielska B, Laloo R, Flodby P, Borok Z, Crandall ED, Thickett DR, Watson SP. Lax S, et al. Among authors: grygielska b. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1016-L1029. doi: 10.1152/ajplung.00023.2017. Epub 2017 Aug 24. Am J Physiol Lung Cell Mol Physiol. 2017. PMID: 28839100 Free PMC article.
The podoplanin-CLEC-2 axis inhibits inflammation in sepsis.
Rayes J, Lax S, Wichaiyo S, Watson SK, Di Y, Lombard S, Grygielska B, Smith SW, Skordilis K, Watson SP. Rayes J, et al. Among authors: grygielska b. Nat Commun. 2017 Dec 21;8(1):2239. doi: 10.1038/s41467-017-02402-6. Nat Commun. 2017. PMID: 29269852 Free PMC article.
Loss of mDia1 and Fhod1 impacts platelet formation but not platelet function.
Zuidscherwoude M, Haining EJ, Simms VA, Watson S, Grygielska B, Hardy AT, Bacon A, Watson SP, Thomas SG. Zuidscherwoude M, et al. Among authors: grygielska b. Platelets. 2021 Nov 17;32(8):1051-1062. doi: 10.1080/09537104.2020.1822522. Epub 2020 Sep 27. Platelets. 2021. PMID: 32981398 Free PMC article.
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