Gruzman A - Search Results

1

Nrf2 Activation by SK-119 Attenuates Oxidative Stress, UVB, and LPS-Induced Damage.

Kahremany S, Babaev I, Gvirtz R, Ogen-Stern N, Azoulay-Ginsburg S, Senderowitz H, Cohen G, Gruzman A. Kahremany S, et al. Among authors: gruzman a. Skin Pharmacol Physiol. 2019;32(4):173-181. doi: 10.1159/000499432. Epub 2019 May 10. Skin Pharmacol Physiol. 2019. PMID: 31079103

2

Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin- and AMPKalpha-independent manner.

Alpert E, Gruzman A, Lardi-Studler B, Cohen G, Reich R, Sasson S. Alpert E, et al. Among authors: gruzman a. Diabetologia. 2006 Mar;49(3):562-70. doi: 10.1007/s00125-005-0122-2. Epub 2006 Jan 31. Diabetologia. 2006. PMID: 16447059

3

The roles of hyperglycaemia and oxidative stress in the rise and collapse of the natural protective mechanism against vascular endothelial cell dysfunction in diabetes.

Cohen G, Riahi Y, Alpert E, Gruzman A, Sasson S. Cohen G, et al. Among authors: gruzman a. Arch Physiol Biochem. 2007 Oct-Dec;113(4-5):259-67. doi: 10.1080/13813450701783513. Arch Physiol Biochem. 2007. PMID: 18158647 Review.

4

Novel D-xylose derivatives stimulate muscle glucose uptake by activating AMP-activated protein kinase alpha.

Gruzman A, Shamni O, Ben Yakir M, Sandovski D, Elgart A, Alpert E, Cohen G, Hoffman A, Katzhendler Y, Cerasi E, Sasson S. Gruzman A, et al. J Med Chem. 2008 Dec 25;51(24):8096-108. doi: 10.1021/jm8008713. J Med Chem. 2008. PMID: 19049348

5

The natural protective mechanism against hyperglycemia in vascular endothelial cells: roles of the lipid peroxidation product 4-hydroxydodecadienal and peroxisome proliferator-activated receptor delta.

Riahi Y, Sin-Malia Y, Cohen G, Alpert E, Gruzman A, Eckel J, Staels B, Guichardant M, Sasson S. Riahi Y, et al. Among authors: gruzman a. Diabetes. 2010 Apr;59(4):808-18. doi: 10.2337/db09-1207. Epub 2010 Jan 27. Diabetes. 2010. PMID: 20107107 Free PMC article.

6

Antihyperglycaemic activity of 2,4:3,5-dibenzylidene-D-xylose-diethyl dithioacetal in diabetic mice.

Gruzman A, Elgart A, Viskind O, Billauer H, Dotan S, Cohen G, Mishani E, Hoffman A, Cerasi E, Sasson S. Gruzman A, et al. J Cell Mol Med. 2012 Mar;16(3):594-604. doi: 10.1111/j.1582-4934.2011.01340.x. J Cell Mol Med. 2012. PMID: 21564514 Free PMC article.

7

Synthesis and mechanism of hypoglycemic activity of benzothiazole derivatives.

Meltzer-Mats E, Babai-Shani G, Pasternak L, Uritsky N, Getter T, Viskind O, Eckel J, Cerasi E, Senderowitz H, Sasson S, Gruzman A. Meltzer-Mats E, et al. Among authors: gruzman a. J Med Chem. 2013 Jul 11;56(13):5335-50. doi: 10.1021/jm4001488. Epub 2013 Jun 26. J Med Chem. 2013. PMID: 23750537

8

Activation of PPARδ: from computer modelling to biological effects.

Kahremany S, Livne A, Gruzman A, Senderowitz H, Sasson S. Kahremany S, et al. Among authors: gruzman a. Br J Pharmacol. 2015 Feb;172(3):754-70. doi: 10.1111/bph.12950. Epub 2014 Dec 15. Br J Pharmacol. 2015. PMID: 25255770 Free PMC article. Review.

9

A chemical chaperone-based drug candidate is effective in a mouse model of amyotrophic lateral sclerosis (ALS).

Getter T, Zaks I, Barhum Y, Ben-Zur T, Böselt S, Gregoire S, Viskind O, Shani T, Gottlieb H, Green O, Shubely M, Senderowitz H, Israelson A, Kwon I, Petri S, Offen D, Gruzman A. Getter T, et al. Among authors: gruzman a. ChemMedChem. 2015 May;10(5):850-61. doi: 10.1002/cmdc.201500045. Epub 2015 Mar 13. ChemMedChem. 2015. PMID: 25772747

10

A DJ-1 Based Peptide Attenuates Dopaminergic Degeneration in Mice Models of Parkinson's Disease via Enhancing Nrf2.

Lev N, Barhum Y, Ben-Zur T, Aharony I, Trifonov L, Regev N, Melamed E, Gruzman A, Offen D. Lev N, et al. Among authors: gruzman a. PLoS One. 2015 May 29;10(5):e0127549. doi: 10.1371/journal.pone.0127549. eCollection 2015. PLoS One. 2015. PMID: 26024237 Free PMC article.

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