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Multivalent interactions essential for lentiviral integrase function.
Ballandras-Colas A, Chivukula V, Gruszka DT, Shan Z, Singh PK, Pye VE, McLean RK, Bedwell GJ, Li W, Nans A, Cook NJ, Fadel HJ, Poeschla EM, Griffiths DJ, Vargas J, Taylor IA, Lyumkis D, Yardimci H, Engelman AN, Cherepanov P. Ballandras-Colas A, et al. Among authors: gruszka dt. Nat Commun. 2022 May 3;13(1):2416. doi: 10.1038/s41467-022-29928-8. Nat Commun. 2022. PMID: 35504909 Free PMC article.
Staphylococcal biofilm-forming protein has a contiguous rod-like structure.
Gruszka DT, Wojdyla JA, Bingham RJ, Turkenburg JP, Manfield IW, Steward A, Leech AP, Geoghegan JA, Foster TJ, Clarke J, Potts JR. Gruszka DT, et al. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):E1011-8. doi: 10.1073/pnas.1119456109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493247 Free PMC article.
Disorder drives cooperative folding in a multidomain protein.
Gruszka DT, Mendonça CA, Paci E, Whelan F, Hawkhead J, Potts JR, Clarke J. Gruszka DT, et al. Proc Natl Acad Sci U S A. 2016 Oct 18;113(42):11841-11846. doi: 10.1073/pnas.1608762113. Epub 2016 Oct 3. Proc Natl Acad Sci U S A. 2016. PMID: 27698144 Free PMC article.
Biochemistry: one molecule at a time.
Gruszka DT. Gruszka DT. Essays Biochem. 2021 Apr 16;65(1):1-3. doi: 10.1042/EBC20210015. Essays Biochem. 2021. PMID: 33860798 Free PMC article.
Sister chromatid cohesion establishment during DNA replication termination.
Cameron G, Gruszka DT, Gruar R, Xie S, Kaya Ç, Nasmyth KA, Baxter J, Srinivasan M, Yardimci H. Cameron G, et al. Among authors: gruszka dt. Science. 2024 Apr 5;384(6691):119-124. doi: 10.1126/science.adf0224. Epub 2024 Mar 14. Science. 2024. PMID: 38484038 Free PMC article.