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Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis.
Roe JS, Hwang CI, Somerville TDD, Milazzo JP, Lee EJ, Da Silva B, Maiorino L, Tiriac H, Young CM, Miyabayashi K, Filippini D, Creighton B, Burkhart RA, Buscaglia JM, Kim EJ, Grem JL, Lazenby AJ, Grunkemeyer JA, Hollingsworth MA, Grandgenett PM, Egeblad M, Park Y, Tuveson DA, Vakoc CR. Roe JS, et al. Among authors: grunkemeyer ja. Cell. 2017 Aug 24;170(5):875-888.e20. doi: 10.1016/j.cell.2017.07.007. Epub 2017 Jul 27. Cell. 2017. PMID: 28757253 Free PMC article.
Isoforms of MUC16 activate oncogenic signaling through EGF receptors to enhance the progression of pancreatic cancer.
Thomas D, Sagar S, Liu X, Lee HR, Grunkemeyer JA, Grandgenett PM, Caffrey T, O'Connell KA, Swanson B, Marcos-Silva L, Steentoft C, Wandall HH, Maurer HC, Peng XL, Yeh JJ, Qiu F, Yu F, Madiyalakan R, Olive KP, Mandel U, Clausen H, Hollingsworth MA, Radhakrishnan P. Thomas D, et al. Among authors: grunkemeyer ja. Mol Ther. 2021 Apr 7;29(4):1557-1571. doi: 10.1016/j.ymthe.2020.12.029. Epub 2020 Dec 25. Mol Ther. 2021. PMID: 33359791 Free PMC article.
IgE-Based Therapeutic Combination Enhances Antitumor Response in Preclinical Models of Pancreatic Cancer.
Markov SD, Caffrey TC, O'Connell KA, Grunkemeyer JA, Shin S, Hanson R, Patil PP, Shukla SK, Gonzalez D, Crawford AJ, Vance KE, Huang Y, Eberle KC, Radhakrishnan P, Grandgenett PM, Singh PK, Madiyalakan R, Daniels-Wells TR, Penichet ML, Nicodemus CF, Poole JA, Jaffee EM, Hollingsworth MA, Mehla K. Markov SD, et al. Among authors: grunkemeyer ja. Mol Cancer Ther. 2021 Dec;20(12):2457-2468. doi: 10.1158/1535-7163.MCT-21-0368. Epub 2021 Oct 8. Mol Cancer Ther. 2021. PMID: 34625505 Free PMC article.
Mucin-1 is required for Coxsackie Virus B3-induced inflammation in pancreatitis.
Liu X, Clemens DL, Grunkemeyer JA, Price JD, O'Connell K, Chapman NM, Storz P, Wen H, Cox JL, Reid WL, Hollingsworth MA, Thayer S. Liu X, et al. Among authors: grunkemeyer ja. Sci Rep. 2019 Jul 23;9(1):10656. doi: 10.1038/s41598-019-46933-y. Sci Rep. 2019. PMID: 31337812 Free PMC article.
Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors.
Mehla K, Tremayne J, Grunkemeyer JA, O'Connell KA, Steele MM, Caffrey TC, Zhu X, Yu F, Singh PK, Schultes BC, Madiyalakan R, Nicodemus CF, Hollingsworth MA. Mehla K, et al. Among authors: grunkemeyer ja. Cancer Immunol Immunother. 2018 Mar;67(3):445-457. doi: 10.1007/s00262-017-2095-7. Epub 2017 Dec 4. Cancer Immunol Immunother. 2018. PMID: 29204701 Free PMC article.
Modular retro-vectors for transgenic and therapeutic use.
Solaiman F, Zink MA, Xu G, Grunkemeyer J, Cosgrove D, Saenz J, Hodgson CP. Solaiman F, et al. Mol Reprod Dev. 2000 Jun;56(2 Suppl):309-15. doi: 10.1002/(SICI)1098-2795(200006)56:2+<309::AID-MRD22>3.0.CO;2-Y. Mol Reprod Dev. 2000. PMID: 10824992 Review.
Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome.
Cosgrove D, Meehan DT, Grunkemeyer JA, Kornak JM, Sayers R, Hunter WJ, Samuelson GC. Cosgrove D, et al. Among authors: grunkemeyer ja. Genes Dev. 1996 Dec 1;10(23):2981-92. doi: 10.1101/gad.10.23.2981. Genes Dev. 1996. PMID: 8956999 Free article.
17 results