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Single-cell RNA sequencing uncovers the nuclear decoy lincRNA PIRAT as a regulator of systemic monocyte immunity during COVID-19.
Aznaourova M, Schmerer N, Janga H, Zhang Z, Pauck K, Bushe J, Volkers SM, Wendisch D, Georg P, Ntini E, Aillaud M, Gündisch M, Mack E, Skevaki C, Keller C, Bauer C, Bertrams W, Marsico A, Nist A, Stiewe T, Gruber AD, Ruppert C, Li Y, Garn H, Sander LE, Schmeck B, Schulte LN. Aznaourova M, et al. Among authors: gruber ad. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2120680119. doi: 10.1073/pnas.2120680119. Epub 2022 Aug 23. Proc Natl Acad Sci U S A. 2022. PMID: 35998224 Free PMC article.
Molecular quantification of canine specific microRNA species.
von Deetzen MC, Schmeck B, Gruber AD, Klopfleisch R. von Deetzen MC, et al. Among authors: gruber ad. Res Vet Sci. 2013 Oct;95(2):562-8. doi: 10.1016/j.rvsc.2013.06.012. Epub 2013 Jul 22. Res Vet Sci. 2013. PMID: 23886399
IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid.
Naujoks J, Tabeling C, Dill BD, Hoffmann C, Brown AS, Kunze M, Kempa S, Peter A, Mollenkopf HJ, Dorhoi A, Kershaw O, Gruber AD, Sander LE, Witzenrath M, Herold S, Nerlich A, Hocke AC, van Driel I, Suttorp N, Bedoui S, Hilbi H, Trost M, Opitz B. Naujoks J, et al. Among authors: gruber ad. PLoS Pathog. 2016 Feb 1;12(2):e1005408. doi: 10.1371/journal.ppat.1005408. eCollection 2016 Feb. PLoS Pathog. 2016. PMID: 26829557 Free PMC article.
Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.
Gutbier B, Schönrock SM, Ehrler C, Haberberger R, Dietert K, Gruber AD, Kummer W, Michalick L, Kuebler WM, Hocke AC, Szymanski K, Letsiou E, Lüth A, Schumacher F, Kleuser B, Mitchell TJ, Bertrams W, Schmeck B, Treue D, Klauschen F, Bauer TT, Tönnies M, Weissmann N, Hippenstiel S, Suttorp N, Witzenrath M; CAPNETZ Study Group. Gutbier B, et al. Among authors: gruber ad. Crit Care Med. 2018 Mar;46(3):e258-e267. doi: 10.1097/CCM.0000000000002916. Crit Care Med. 2018. PMID: 29298188
Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.
Ugolini M, Gerhard J, Burkert S, Jensen KJ, Georg P, Ebner F, Volkers SM, Thada S, Dietert K, Bauer L, Schäfer A, Helbig ET, Opitz B, Kurth F, Sur S, Dittrich N, Gaddam S, Conrad ML, Benn CS, Blohm U, Gruber AD, Hutloff A, Hartmann S, Boekschoten MV, Müller M, Jungersen G, Schumann RR, Suttorp N, Sander LE. Ugolini M, et al. Among authors: gruber ad. Nat Immunol. 2018 Apr;19(4):386-396. doi: 10.1038/s41590-018-0068-4. Epub 2018 Mar 19. Nat Immunol. 2018. PMID: 29556002
ADAR1 Is Required for Dendritic Cell Subset Homeostasis and Alveolar Macrophage Function.
Baal N, Cunningham S, Obermann HL, Thomas J, Lippitsch A, Dietert K, Gruber AD, Kaufmann A, Michel G, Nist A, Stiewe T, Rupp O, Goesmann A, Zukunft S, Fleming I, Bein G, Lohmeyer J, Bauer S, Hackstein H. Baal N, et al. Among authors: gruber ad. J Immunol. 2019 Feb 15;202(4):1099-1111. doi: 10.4049/jimmunol.1800269. Epub 2019 Jan 16. J Immunol. 2019. PMID: 30651342
Peptidoglycan Recognition Protein 4 Limits Bacterial Clearance and Inflammation in Lungs by Control of the Gut Microbiota.
Dabrowski AN, Shrivastav A, Conrad C, Komma K, Weigel M, Dietert K, Gruber AD, Bertrams W, Wilhelm J, Schmeck B, Reppe K, N'Guessan PD, Aly S, Suttorp N, Hain T, Zahlten J. Dabrowski AN, et al. Among authors: gruber ad. Front Immunol. 2019 Sep 20;10:2106. doi: 10.3389/fimmu.2019.02106. eCollection 2019. Front Immunol. 2019. PMID: 31616404 Free PMC article.
Noncoding RNA MaIL1 is an integral component of the TLR4-TRIF pathway.
Aznaourova M, Janga H, Sefried S, Kaufmann A, Dorna J, Volkers SM, Georg P, Lechner M, Hoppe J, Dökel S, Schmerer N, Gruber AD, Linne U, Bauer S, Sander LE, Schmeck B, Schulte LN. Aznaourova M, et al. Among authors: gruber ad. Proc Natl Acad Sci U S A. 2020 Apr 21;117(16):9042-9053. doi: 10.1073/pnas.1920393117. Epub 2020 Apr 2. Proc Natl Acad Sci U S A. 2020. PMID: 32241891 Free PMC article.
Cyclophilin inhibitors restrict Middle East respiratory syndrome coronavirus via interferon-λ in vitro and in mice.
Sauerhering L, Kupke A, Meier L, Dietzel E, Hoppe J, Gruber AD, Gattenloehner S, Witte B, Fink L, Hofmann N, Zimmermann T, Goesmann A, Nist A, Stiewe T, Becker S, Herold S, Peteranderl C. Sauerhering L, et al. Among authors: gruber ad. Eur Respir J. 2020 Nov 26;56(5):1901826. doi: 10.1183/13993003.01826-2019. Print 2020 Nov. Eur Respir J. 2020. PMID: 32616594 Free PMC article.
317 results