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101 results

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Chronic airway epithelial hypoxia exacerbates injury in muco-obstructive lung disease through mucus hyperconcentration.
Mikami Y, Grubb BR, Rogers TD, Dang H, Asakura T, Kota P, Gilmore RC, Okuda K, Morton LC, Sun L, Chen G, Wykoff JA, Ehre C, Vilar J, van Heusden C, Livraghi-Butrico A, Gentzsch M, Button B, Stutts MJ, Randell SH, O'Neal WK, Boucher RC. Mikami Y, et al. Among authors: grubb br. Sci Transl Med. 2023 Jun 7;15(699):eabo7728. doi: 10.1126/scitranslmed.abo7728. Epub 2023 Jun 7. Sci Transl Med. 2023. PMID: 37285404
BPIFB1 loss alters airway mucus properties and diminishes mucociliary clearance.
Donoghue LJ, Markovetz MR, Morrison CB, Chen G, McFadden KM, Sadritabrizi T, Gutay MI, Kato T, Rogers TD, Snead JY, Livraghi-Butrico A, Button B, Ehre C, Grubb BR, Hill DB, Kelada SNP. Donoghue LJ, et al. Among authors: grubb br. Am J Physiol Lung Cell Mol Physiol. 2023 Dec 1;325(6):L765-L775. doi: 10.1152/ajplung.00390.2022. Epub 2023 Oct 17. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37847709
Prolonged airway explant culture enables study of health, disease, and viral pathogenesis.
Lee-Ferris RE, Okuda K, Galiger JR, Schworer SA, Rogers TD, Dang H, Gilmore R, Edwards C, Nakano S, Cawley AM, Pickles RJ, Gallant SC, Crisci E, Rivier L, Hagood JS, O'Neal WK, Baric RS, Grubb BR, Boucher RC, Randell SH. Lee-Ferris RE, et al. Among authors: grubb br. bioRxiv [Preprint]. 2024 Feb 5:2024.02.03.578756. doi: 10.1101/2024.02.03.578756. bioRxiv. 2024. PMID: 38370820 Free PMC article. Preprint.
Regional Differences in Mucociliary Clearance in the Upper and Lower Airways.
Rogers TD, Button B, Kelada SNP, Ostrowski LE, Livraghi-Butrico A, Gutay MI, Esther CR Jr, Grubb BR. Rogers TD, et al. Among authors: grubb br. Front Physiol. 2022 Mar 9;13:842592. doi: 10.3389/fphys.2022.842592. eCollection 2022. Front Physiol. 2022. PMID: 35356083 Free PMC article.
Reuse of Cell Culture Inserts for In Vitro Human Primary Airway Epithelial Cell Studies.
Kato T, Mikami Y, Sun L, Rogers TD, Grubb BR, Morrison CB, Ehre C, Sears PR, Ostrowski LE, Randell SH, Boucher RC. Kato T, et al. Among authors: grubb br. Am J Respir Cell Mol Biol. 2021 Jun;64(6):760-764. doi: 10.1165/rcmb.2021-0033LE. Am J Respir Cell Mol Biol. 2021. PMID: 33788673 Free PMC article. No abstract available.
Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia.
Okuda K, Dang H, Kobayashi Y, Carraro G, Nakano S, Chen G, Kato T, Asakura T, Gilmore RC, Morton LC, Lee RE, Mascenik T, Yin WN, Barbosa Cardenas SM, O'Neal YK, Minnick CE, Chua M, Quinney NL, Gentzsch M, Anderson CW, Ghio A, Matsui H, Nagase T, Ostrowski LE, Grubb BR, Olsen JC, Randell SH, Stripp BR, Tata PR, O'Neal WK, Boucher RC. Okuda K, et al. Among authors: grubb br. Am J Respir Crit Care Med. 2021 May 15;203(10):1275-1289. doi: 10.1164/rccm.202008-3198OC. Am J Respir Crit Care Med. 2021. PMID: 33321047 Free PMC article.
Phenotypes of CF rabbits generated by CRISPR/Cas9-mediated disruption of the CFTR gene.
Xu J, Livraghi-Butrico A, Hou X, Rajagopalan C, Zhang J, Song J, Jiang H, Wei HG, Wang H, Bouhamdan M, Ruan J, Yang D, Qiu Y, Xie Y, Barrett R, McClellan S, Mou H, Wu Q, Chen X, Rogers TD, Wilkinson KJ, Gilmore RC, Esther CR Jr, Zaman K, Liang X, Sobolic M, Hazlett L, Zhang K, Frizzell RA, Gentzsch M, O'Neal WK, Grubb BR, Chen YE, Boucher RC, Sun F. Xu J, et al. Among authors: grubb br. JCI Insight. 2021 Jan 11;6(1):e139813. doi: 10.1172/jci.insight.139813. JCI Insight. 2021. PMID: 33232302 Free PMC article.
101 results