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The new epoch of structural insights into radical SAM enzymology.
Lachowicz J, Lee J, Sagatova A, Jew K, Grove TL. Lachowicz J, et al. Among authors: grove tl. Curr Opin Struct Biol. 2023 Dec;83:102720. doi: 10.1016/j.sbi.2023.102720. Epub 2023 Oct 18. Curr Opin Struct Biol. 2023. PMID: 37862762 Review.
CMPK2 restricts Zika virus replication by inhibiting viral translation.
Pawlak JB, Hsu JC, Xia H, Han P, Suh HW, Grove TL, Morrison J, Shi PY, Cresswell P, Laurent-Rolle M. Pawlak JB, et al. Among authors: grove tl. PLoS Pathog. 2023 Apr 19;19(4):e1011286. doi: 10.1371/journal.ppat.1011286. eCollection 2023 Apr. PLoS Pathog. 2023. PMID: 37075076 Free PMC article.
Integrative Molecular Structure Elucidation and Construction of an Extended Metabolic Pathway Associated with an Ancient Innate Immune Response in COVID-19 Patients.
Sala S, Nitschke P, Masuda R, Gray N, Lawler NG, Wood JM, Buckler JN, Berezhnoy G, Bolaños J, Boughton BA, Lonati C, Rössler T, Singh Y, Wilson ID, Lodge S, Morillon AC, Loo RL, Hall D, Whiley L, Evans GB, Grove TL, Almo SC, Harris LD, Holmes E, Merle U, Trautwein C, Nicholson JK, Wist J. Sala S, et al. Among authors: grove tl. J Proteome Res. 2024 Mar 1;23(3):956-970. doi: 10.1021/acs.jproteome.3c00654. Epub 2024 Feb 4. J Proteome Res. 2024. PMID: 38310443 Free PMC article.
Inhibition of SARS-CoV-2 polymerase by nucleotide analogs from a single-molecule perspective.
Seifert M, Bera SC, van Nies P, Kirchdoerfer RN, Shannon A, Le TT, Meng X, Xia H, Wood JM, Harris LD, Papini FS, Arnold JJ, Almo S, Grove TL, Shi PY, Xiang Y, Canard B, Depken M, Cameron CE, Dulin D. Seifert M, et al. Among authors: grove tl. Elife. 2021 Oct 7;10:e70968. doi: 10.7554/eLife.70968. Elife. 2021. PMID: 34617885 Free PMC article.
Structural basis for tRNA methylthiolation by the radical SAM enzyme MiaB.
Esakova OA, Grove TL, Yennawar NH, Arcinas AJ, Wang B, Krebs C, Almo SC, Booker SJ. Esakova OA, et al. Among authors: grove tl. Nature. 2021 Sep;597(7877):566-570. doi: 10.1038/s41586-021-03904-6. Epub 2021 Sep 15. Nature. 2021. PMID: 34526715 Free PMC article.
59 results