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Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids.
Meng Q, Xie S, Gray GK, Dezfulian MH, Li W, Huang L, Akshinthala D, Ferrer E, Conahan C, Perea Del Pino S, Grossman J, Elledge SJ, Hidalgo M, Muthuswamy SK. Meng Q, et al. Among authors: grossman j. J Immunother Cancer. 2021 Nov;9(11):e003213. doi: 10.1136/jitc-2021-003213. J Immunother Cancer. 2021. PMID: 34789550 Free PMC article.
PDX-derived organoids model in vivo drug response and secrete biomarkers.
Huang L, Bockorny B, Paul I, Akshinthala D, Frappart PO, Gandarilla O, Bose A, Sanchez-Gonzalez V, Rouse EE, Lehoux SD, Pandell N, Lim CM, Clohessy JG, Grossman J, Gonzalez R, Del Pino SP, Daaboul G, Sawhney MS, Freedman SD, Kleger A, Cummings RD, Emili A, Muthuswamy LB, Hidalgo M, Muthuswamy SK. Huang L, et al. Among authors: grossman j. JCI Insight. 2020 Nov 5;5(21):e135544. doi: 10.1172/jci.insight.135544. JCI Insight. 2020. PMID: 32990680 Free PMC article.
Organoid Sensitivity Correlates with Therapeutic Response in Patients with Pancreatic Cancer.
Grossman JE, Muthuswamy L, Huang L, Akshinthala D, Perea S, Gonzalez RS, Tsai LL, Cohen J, Bockorny B, Bullock AJ, Schlechter B, Peters MLB, Conahan C, Narasimhan S, Lim C, Davis RB, Besaw R, Sawhney MS, Pleskow D, Berzin TM, Smith M, Kent TS, Callery M, Muthuswamy SK, Hidalgo M. Grossman JE, et al. Clin Cancer Res. 2022 Feb 15;28(4):708-718. doi: 10.1158/1078-0432.CCR-20-4116. Clin Cancer Res. 2022. PMID: 34789479 Free PMC article.
Facts and Hopes in Immunotherapy of Pancreatic Cancer.
Bockorny B, Grossman JE, Hidalgo M. Bockorny B, et al. Clin Cancer Res. 2022 Nov 1;28(21):4606-4617. doi: 10.1158/1078-0432.CCR-21-3452. Clin Cancer Res. 2022. PMID: 35775964 Review.
A Preclinical and Phase Ib Study of Palbociclib plus Nab-Paclitaxel in Patients with Metastatic Adenocarcinoma of the Pancreas.
Hidalgo M, Garcia-Carbonero R, Lim KH, Messersmith WA, Garrido-Laguna I, Borazanci E, Lowy AM, Medina Rodriguez L, Laheru D, Salvador-Barbero B, Malumbres M, Shields DJ, Grossman JE, Huang X, Tammaro M, Martini JF, Yu Y, Kern K, Macarulla T. Hidalgo M, et al. Among authors: grossman je. Cancer Res Commun. 2022 Nov 2;2(11):1326-1333. doi: 10.1158/2767-9764.CRC-22-0072. eCollection 2022 Nov. Cancer Res Commun. 2022. PMID: 36970055 Free PMC article. Clinical Trial.
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