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A proteogenomic signature of age-related macular degeneration in blood.
Emilsson V, Gudmundsson EF, Jonmundsson T, Jonsson BG, Twarog M, Gudmundsdottir V, Li Z, Finkel N, Poor S, Liu X, Esterberg R, Zhang Y, Jose S, Huang CL, Liao SM, Loureiro J, Zhang Q, Grosskreutz CL, Nguyen AA, Huang Q, Leehy B, Pitts R, Aspelund T, Lamb JR, Jonasson F, Launer LJ, Cotch MF, Jennings LL, Gudnason V, Walshe TE. Emilsson V, et al. Among authors: grosskreutz cl. Nat Commun. 2022 Jun 13;13(1):3401. doi: 10.1038/s41467-022-31085-x. Nat Commun. 2022. PMID: 35697682 Free PMC article.
Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration.
Crowley MA, Garland DL, Sellner H, Banks A, Fan L, Rejtar T, Buchanan N, Delgado O, Xu YY, Jose S, Adams CM, Mogi M, Wang K, Bigelow CE, Poor S, Anderson K, Jaffee BD, Prasanna G, Grosskreutz C, Fernandez-Godino R, Pierce EA, Dryja TP, Liao SM. Crowley MA, et al. Hum Mol Genet. 2023 Jan 6;32(2):204-217. doi: 10.1093/hmg/ddac187. Hum Mol Genet. 2023. PMID: 35943778 Free PMC article.
A Randomized, Double-Masked, Multicenter Trial of Topical Acrizanib (LHA510), a Tyrosine Kinase VEGF-Receptor Inhibitor, in Treatment-Experienced Subjects With Neovascular Age-Related Macular Degeneration.
Poor SH, Weissgerber G, Adams CM, Bhatt H, Browning DJ, Chastain J, Ciulla TA, Ferriere M, Gedif K, Glazer LC, Joondeph BC, Normand G, Sheth V, Watters C, Grosskreutz CL. Poor SH, et al. Among authors: grosskreutz cl. Am J Ophthalmol. 2022 Jul;239:180-189. doi: 10.1016/j.ajo.2022.02.019. Epub 2022 Mar 2. Am J Ophthalmol. 2022. PMID: 35247334 Free article. Clinical Trial.
Glaucoma - Next Generation Therapeutics: Impossible to Possible.
Adams CM, Stacy R, Rangaswamy N, Bigelow C, Grosskreutz CL, Prasanna G. Adams CM, et al. Among authors: grosskreutz cl. Pharm Res. 2018 Dec 13;36(2):25. doi: 10.1007/s11095-018-2557-4. Pharm Res. 2018. PMID: 30547244 Review.
78 results