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Active Wnt proteins are secreted on exosomes.
Gross JC, Chaudhary V, Bartscherer K, Boutros M. Gross JC, et al. Nat Cell Biol. 2012 Oct;14(10):1036-45. doi: 10.1038/ncb2574. Epub 2012 Sep 16. Nat Cell Biol. 2012. PMID: 22983114
Biochemical Methods to Analyze Wnt Protein Secretion.
Glaeser K, Boutros M, Gross JC. Glaeser K, et al. Among authors: gross jc. Methods Mol Biol. 2016;1481:17-28. doi: 10.1007/978-1-4939-6393-5_3. Methods Mol Biol. 2016. PMID: 27590148
miR-10a-5p and miR-29b-3p as Extracellular Vesicle-Associated Prostate Cancer Detection Markers.
Worst TS, Previti C, Nitschke K, Diessl N, Gross JC, Hoffmann L, Frey L, Thomas V, Kahlert C, Bieback K, Crigna AT, Fricke F, Porubsky S, Westhoff N, Hardenberg JV, Nuhn P, Erben P, Michel MS, Boutros M. Worst TS, et al. Among authors: gross jc. Cancers (Basel). 2019 Dec 21;12(1):43. doi: 10.3390/cancers12010043. Cancers (Basel). 2019. PMID: 31877768 Free PMC article.
eGFP-tagged Wnt-3a enables functional analysis of Wnt trafficking and signaling and kinetic assessment of Wnt binding to full-length Frizzled.
Wesslowski J, Kozielewicz P, Wang X, Cui H, Schihada H, Kranz D, Karuna M P, Levkin P, Gross JC, Boutros M, Schulte G, Davidson G. Wesslowski J, et al. Among authors: gross jc. J Biol Chem. 2020 Jun 26;295(26):8759-8774. doi: 10.1074/jbc.RA120.012892. Epub 2020 May 7. J Biol Chem. 2020. PMID: 32381507 Free PMC article.
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