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TRPM8 inhibits endothelial cell migration via a non-channel function by trapping the small GTPase Rap1.
Genova T, Grolez GP, Camillo C, Bernardini M, Bokhobza A, Richard E, Scianna M, Lemonnier L, Valdembri D, Munaron L, Philips MR, Mattot V, Serini G, Prevarskaya N, Gkika D, Pla AF. Genova T, et al. Among authors: grolez gp. J Cell Biol. 2017 Jul 3;216(7):2107-2130. doi: 10.1083/jcb.201506024. Epub 2017 May 26. J Cell Biol. 2017. PMID: 28550110 Free PMC article.
TRPM8 and prostate: a cold case?
Noyer L, Grolez GP, Prevarskaya N, Gkika D, Lemonnier L. Noyer L, et al. Among authors: grolez gp. Pflugers Arch. 2018 Oct;470(10):1419-1429. doi: 10.1007/s00424-018-2169-1. Epub 2018 Jun 20. Pflugers Arch. 2018. PMID: 29926226 Review.
TRPM8 Puts the Chill on Prostate Cancer.
Grolez GP, Gkika D. Grolez GP, et al. Pharmaceuticals (Basel). 2016 Jul 9;9(3):44. doi: 10.3390/ph9030044. Pharmaceuticals (Basel). 2016. PMID: 27409624 Free PMC article. Review.
Transient Receptor Potential Channel Expression Signatures in Tumor-Derived Endothelial Cells: Functional Roles in Prostate Cancer Angiogenesis.
Bernardini M, Brossa A, Chinigo G, Grolez GP, Trimaglio G, Allart L, Hulot A, Marot G, Genova T, Joshi A, Mattot V, Fromont G, Munaron L, Bussolati B, Prevarskaya N, Fiorio Pla A, Gkika D. Bernardini M, et al. Among authors: grolez gp. Cancers (Basel). 2019 Jul 8;11(7):956. doi: 10.3390/cancers11070956. Cancers (Basel). 2019. PMID: 31288452 Free PMC article.
TRPM8 as an Anti-Tumoral Target in Prostate Cancer Growth and Metastasis Dissemination.
Grolez GP, Chinigò G, Barras A, Hammadi M, Noyer L, Kondratska K, Bulk E, Oullier T, Marionneau-Lambot S, Le Mée M, Rétif S, Lerondel S, Bongiovanni A, Genova T, Roger S, Boukherroub R, Schwab A, Fiorio Pla A, Gkika D. Grolez GP, et al. Int J Mol Sci. 2022 Jun 15;23(12):6672. doi: 10.3390/ijms23126672. Int J Mol Sci. 2022. PMID: 35743115 Free PMC article.
TRPM8-Rap1A Interaction Sites as Critical Determinants for Adhesion and Migration of Prostate and Other Epithelial Cancer Cells.
Chinigò G, Grolez GP, Audero M, Bokhobza A, Bernardini M, Cicero J, Toillon RA, Bailleul Q, Visentin L, Ruffinatti FA, Brysbaert G, Lensink MF, De Ruyck J, Cantelmo AR, Fiorio Pla A, Gkika D. Chinigò G, et al. Among authors: grolez gp. Cancers (Basel). 2022 Apr 30;14(9):2261. doi: 10.3390/cancers14092261. Cancers (Basel). 2022. PMID: 35565390 Free PMC article.
Testosterone-androgen receptor: The steroid link inhibiting TRPM8-mediated cold sensitivity.
Gkika D, Lolignier S, Grolez GP, Bavencoffe A, Shapovalov G, Gordienko D, Kondratskyi A, Meleine M, Prival L, Chapuy E, Etienne M, Eschalier A, Shuba Y, Skryma R, Busserolles J, Prevarskaya N. Gkika D, et al. Among authors: grolez gp. FASEB J. 2020 Jun;34(6):7483-7499. doi: 10.1096/fj.201902270R. Epub 2020 Apr 11. FASEB J. 2020. PMID: 32277850
13 results