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In vivo and in silico dynamics of the development of Metabolic Syndrome.
Rozendaal YJW, Wang Y, Paalvast Y, Tambyrajah LL, Li Z, Willems van Dijk K, Rensen PCN, Kuivenhoven JA, Groen AK, Hilbers PAJ, van Riel NAW. Rozendaal YJW, et al. Among authors: groen ak. PLoS Comput Biol. 2018 Jun 7;14(6):e1006145. doi: 10.1371/journal.pcbi.1006145. eCollection 2018 Jun. PLoS Comput Biol. 2018. PMID: 29879115 Free PMC article.
ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis.
Schaap FG, Rensen PC, Voshol PJ, Vrins C, van der Vliet HN, Chamuleau RA, Havekes LM, Groen AK, van Dijk KW. Schaap FG, et al. Among authors: groen ak. J Biol Chem. 2004 Jul 2;279(27):27941-7. doi: 10.1074/jbc.M403240200. Epub 2004 Apr 16. J Biol Chem. 2004. PMID: 15090553 Free article.
Reduced fecal sterol excretion in subjects with familial hypoalphalipoproteinemia.
Harchaoui KE, Franssen R, Hovingh GK, Bisoendial RJ, Stellaard F, Kuipers F, Kastelein JJ, Kuivenhoven JA, Stroes ES, Groen AK. Harchaoui KE, et al. Among authors: groen ak. Atherosclerosis. 2009 Dec;207(2):614-6. doi: 10.1016/j.atherosclerosis.2009.06.022. Epub 2009 Jun 18. Atherosclerosis. 2009. PMID: 19616211
Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.
Bietrix F, Lombardo E, van Roomen CP, Ottenhoff R, Vos M, Rensen PC, Verhoeven AJ, Aerts JM, Groen AK. Bietrix F, et al. Among authors: groen ak. Arterioscler Thromb Vasc Biol. 2010 May;30(5):931-7. doi: 10.1161/ATVBAHA.109.201673. Epub 2010 Feb 18. Arterioscler Thromb Vasc Biol. 2010. PMID: 20167657
Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein.
Vrins CLJ, Ottenhoff R, van den Oever K, de Waart DR, Kruyt JK, Zhao Y, van Berkel TJC, Havekes LM, Aerts JM, van Eck M, Rensen PCN, Groen AK. Vrins CLJ, et al. Among authors: groen ak. J Lipid Res. 2012 Oct;53(10):2017-2023. doi: 10.1194/jlr.M022194. Epub 2012 Jul 16. J Lipid Res. 2012. PMID: 22802462 Free PMC article.
In vivo tissue cholesterol efflux is reduced in carriers of a mutation in APOA1.
Holleboom AG, Jakulj L, Franssen R, Decaris J, Vergeer M, Koetsveld J, Luchoomun J, Glass A, Hellerstein MK, Kastelein JJ, Hovingh GK, Kuivenhoven JA, Groen AK, Turner SM, Stroes ES. Holleboom AG, et al. Among authors: groen ak. J Lipid Res. 2013 Jul;54(7):1964-71. doi: 10.1194/jlr.P028449. Epub 2013 May 6. J Lipid Res. 2013. PMID: 23650622 Free PMC article.
433 results