Gritti A - Search Results

1

Integrated Computational Analysis Highlights unique miRNA Signatures in the Subventricular Zone and Striatum of GM2 Gangliosidosis Animal Models.

Morena F, Oikonomou V, Argentati C, Bazzucchi M, Emiliani C, Gritti A, Martino S. Morena F, et al. Among authors: gritti a. Int J Mol Sci. 2019 Jun 28;20(13):3179. doi: 10.3390/ijms20133179. Int J Mol Sci. 2019. PMID: 31261761 Free PMC article.

2

Novel bicistronic lentiviral vectors correct β-Hexosaminidase deficiency in neural and hematopoietic stem cells and progeny: implications for in vivo and ex vivo gene therapy of GM2 gangliosidosis.

Ornaghi F, Sala D, Tedeschi F, Maffia MC, Bazzucchi M, Morena F, Valsecchi M, Aureli M, Martino S, Gritti A. Ornaghi F, et al. Among authors: gritti a. Neurobiol Dis. 2020 Feb;134:104667. doi: 10.1016/j.nbd.2019.104667. Epub 2019 Nov 1. Neurobiol Dis. 2020. PMID: 31682993 Free article.

3

In vitro Validation of Chimeric β-Galactosylceramidase Enzymes With Improved Enzymatic Activity and Increased Secretion.

Ricca A, Cascino F, Morena F, Martino S, Gritti A. Ricca A, et al. Among authors: gritti a. Front Mol Biosci. 2020 Jul 21;7:167. doi: 10.3389/fmolb.2020.00167. eCollection 2020. Front Mol Biosci. 2020. PMID: 32850960 Free PMC article.

4

Therapeutic advantages of combined gene/cell therapy strategies in a murine model of GM2 gangliosidosis.

Sala D, Ornaghi F, Morena F, Argentati C, Valsecchi M, Alberizzi V, Di Guardo R, Bolino A, Aureli M, Martino S, Gritti A. Sala D, et al. Among authors: gritti a. Mol Ther Methods Clin Dev. 2022 Mar 16;25:170-189. doi: 10.1016/j.omtm.2022.03.011. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35434178 Free PMC article.

5

Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology.

Martino S, di Girolamo I, Cavazzin C, Tiribuzi R, Galli R, Rivaroli A, Valsecchi M, Sandhoff K, Sonnino S, Vescovi A, Gritti A, Orlacchio A. Martino S, et al. Among authors: gritti a. J Neurochem. 2009 Apr;109(1):135-47. doi: 10.1111/j.1471-4159.2009.05919.x. Epub 2009 Feb 20. J Neurochem. 2009. PMID: 19166507 Free article.

6

Therapeutic benefit of lentiviral-mediated neonatal intracerebral gene therapy in a mouse model of globoid cell leukodystrophy.

Lattanzi A, Salvagno C, Maderna C, Benedicenti F, Morena F, Kulik W, Naldini L, Montini E, Martino S, Gritti A. Lattanzi A, et al. Among authors: gritti a. Hum Mol Genet. 2014 Jun 15;23(12):3250-68. doi: 10.1093/hmg/ddu034. Epub 2014 Jan 23. Hum Mol Genet. 2014. PMID: 24463623 Free PMC article.

7

Combined gene/cell therapies provide long-term and pervasive rescue of multiple pathological symptoms in a murine model of globoid cell leukodystrophy.

Ricca A, Rufo N, Ungari S, Morena F, Martino S, Kulik W, Alberizzi V, Bolino A, Bianchi F, Del Carro U, Biffi A, Gritti A. Ricca A, et al. Among authors: gritti a. Hum Mol Genet. 2015 Jun 15;24(12):3372-89. doi: 10.1093/hmg/ddv086. Epub 2015 Mar 5. Hum Mol Genet. 2015. PMID: 25749991 Free PMC article.

8

Pervasive supply of therapeutic lysosomal enzymes in the CNS of normal and Krabbe-affected non-human primates by intracerebral lentiviral gene therapy.

Meneghini V, Lattanzi A, Tiradani L, Bravo G, Morena F, Sanvito F, Calabria A, Bringas J, Fisher-Perkins JM, Dufour JP, Baker KC, Doglioni C, Montini E, Bunnell BA, Bankiewicz K, Martino S, Naldini L, Gritti A. Meneghini V, et al. Among authors: gritti a. EMBO Mol Med. 2016 May 2;8(5):489-510. doi: 10.15252/emmm.201505850. Print 2016 May. EMBO Mol Med. 2016. PMID: 27025653 Free PMC article.

9

A new analytical bench assay for the determination of arylsulfatase a activity toward galactosyl-3-sulfate ceramide: implication for metachromatic leukodystrophy diagnosis.

Morena F, di Girolamo I, Emiliani C, Gritti A, Biffi A, Martino S. Morena F, et al. Among authors: gritti a. Anal Chem. 2014 Jan 7;86(1):473-81. doi: 10.1021/ac4023555. Epub 2013 Dec 11. Anal Chem. 2014. PMID: 24294900

10

Human iPSC-based models highlight defective glial and neuronal differentiation from neural progenitor cells in metachromatic leukodystrophy.

Frati G, Luciani M, Meneghini V, De Cicco S, Ståhlman M, Blomqvist M, Grossi S, Filocamo M, Morena F, Menegon A, Martino S, Gritti A. Frati G, et al. Among authors: gritti a. Cell Death Dis. 2018 Jun 13;9(6):698. doi: 10.1038/s41419-018-0737-0. Cell Death Dis. 2018. PMID: 29899471 Free PMC article.

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