Grimm C - Search Results

1

Endolysosomal Cation Channels and Cancer-A Link with Great Potential.

Grimm C, Bartel K, Vollmar AM, Biel M. Grimm C, et al. Pharmaceuticals (Basel). 2018 Jan 5;11(1):4. doi: 10.3390/ph11010004. Pharmaceuticals (Basel). 2018. PMID: 29303993 Free PMC article. Review.

2

Role of TRPML and two-pore channels in endolysosomal cation homeostasis.

Grimm C, Hassan S, Wahl-Schott C, Biel M. Grimm C, et al. J Pharmacol Exp Ther. 2012 Aug;342(2):236-44. doi: 10.1124/jpet.112.192880. Epub 2012 Apr 19. J Pharmacol Exp Ther. 2012. PMID: 22518024

3

Two-Pore Channels: Catalyzers of Endolysosomal Transport and Function.

Grimm C, Chen CC, Wahl-Schott C, Biel M. Grimm C, et al. Front Pharmacol. 2017 Feb 7;8:45. doi: 10.3389/fphar.2017.00045. eCollection 2017. Front Pharmacol. 2017. PMID: 28223936 Free PMC article. Review.

4

Recombinant tandem of pore-domains in a Weakly Inward rectifying K⁺ channel 2 (TWIK2) forms active lysosomal channels.

Bobak N, Feliciangeli S, Chen CC, Ben Soussia I, Bittner S, Pagnotta S, Ruck T, Biel M, Wahl-Schott C, Grimm C, Meuth SG, Lesage F. Bobak N, et al. Among authors: grimm c. Sci Rep. 2017 Apr 5;7(1):649. doi: 10.1038/s41598-017-00640-8. Sci Rep. 2017. PMID: 28381826 Free PMC article.

5

From mucolipidosis type IV to Ebola: TRPML and two-pore channels at the crossroads of endo-lysosomal trafficking and disease.

Grimm C, Butz E, Chen CC, Wahl-Schott C, Biel M. Grimm C, et al. Cell Calcium. 2017 Nov;67:148-155. doi: 10.1016/j.ceca.2017.04.003. Epub 2017 Apr 23. Cell Calcium. 2017. PMID: 28457591 Review.

6

Patch-clamp technique to characterize ion channels in enlarged individual endolysosomes.

Chen CC, Cang C, Fenske S, Butz E, Chao YK, Biel M, Ren D, Wahl-Schott C, Grimm C. Chen CC, et al. Among authors: grimm c. Nat Protoc. 2017 Aug;12(8):1639-1658. doi: 10.1038/nprot.2017.036. Epub 2017 Jul 20. Nat Protoc. 2017. PMID: 28726848

7

Small Molecules for Early Endosome-Specific Patch Clamping.

Chen CC, Butz ES, Chao YK, Grishchuk Y, Becker L, Heller S, Slaugenhaupt SA, Biel M, Wahl-Schott C, Grimm C. Chen CC, et al. Among authors: grimm c. Cell Chem Biol. 2017 Jul 20;24(7):907-916.e4. doi: 10.1016/j.chembiol.2017.05.025. Cell Chem Biol. 2017. PMID: 28732201 Free article.

8

The two-pore channel TPC1 is required for efficient protein processing through early and recycling endosomes.

Castonguay J, Orth JHC, Müller T, Sleman F, Grimm C, Wahl-Schott C, Biel M, Mallmann RT, Bildl W, Schulte U, Klugbauer N. Castonguay J, et al. Among authors: grimm c. Sci Rep. 2017 Aug 30;7(1):10038. doi: 10.1038/s41598-017-10607-4. Sci Rep. 2017. PMID: 28855648 Free PMC article.

9

TPC2 polymorphisms associated with a hair pigmentation phenotype in humans result in gain of channel function by independent mechanisms.

Chao YK, Schludi V, Chen CC, Butz E, Nguyen ONP, Müller M, Krüger J, Kammerbauer C, Ben-Johny M, Vollmar AM, Berking C, Biel M, Wahl-Schott CA, Grimm C. Chao YK, et al. Among authors: grimm c. Proc Natl Acad Sci U S A. 2017 Oct 10;114(41):E8595-E8602. doi: 10.1073/pnas.1705739114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923947 Free PMC article.

10

Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress.

Barben M, Ail D, Storti F, Klee K, Schori C, Samardzija M, Michalakis S, Biel M, Meneau I, Blaser F, Barthelmes D, Grimm C. Barben M, et al. Among authors: grimm c. Cell Death Differ. 2018 Dec;25(12):2071-2085. doi: 10.1038/s41418-018-0094-7. Epub 2018 Apr 17. Cell Death Differ. 2018. PMID: 29666476 Free PMC article.

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