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Essential role of a ThPOK autoregulatory loop in the maintenance of mature CD4+ T cell identity and function.
Basu J, Reis BS, Peri S, Zha J, Hua X, Ge L, Ferchen K, Nicolas E, Czyzewicz P, Cai KQ, Tan Y, Fuxman Bass JI, Walhout AJM, Grimes HL, Grivennikov SI, Mucida D, Kappes DJ. Basu J, et al. Among authors: grimes hl. Nat Immunol. 2021 Aug;22(8):969-982. doi: 10.1038/s41590-021-00980-8. Epub 2021 Jul 26. Nat Immunol. 2021. PMID: 34312548 Free PMC article.
Counting the cost of lineage decisions.
Yáñez A, Goodridge HS, Grimes HL. Yáñez A, et al. Among authors: grimes hl. Nat Immunol. 2017 Jul 19;18(8):872-873. doi: 10.1038/ni.3794. Nat Immunol. 2017. PMID: 28722717 No abstract available.
Mouse models of neutropenia reveal progenitor-stage-specific defects.
Muench DE, Olsson A, Ferchen K, Pham G, Serafin RA, Chutipongtanate S, Dwivedi P, Song B, Hay S, Chetal K, Trump-Durbin LR, Mookerjee-Basu J, Zhang K, Yu JC, Lutzko C, Myers KC, Nazor KL, Greis KD, Kappes DJ, Way SS, Salomonis N, Grimes HL. Muench DE, et al. Among authors: grimes hl. Nature. 2020 Jun;582(7810):109-114. doi: 10.1038/s41586-020-2227-7. Epub 2020 Apr 22. Nature. 2020. PMID: 32494068 Free PMC article.
ThPOK is a critical multifaceted regulator of myeloid lineage development.
Basu J, Olsson A, Ferchen K, Titerina EK, Chetal K, Nicolas E, Czyzewicz P, Levchenko D, Ge L, Hua X, Grimes HL, Salomonis N, Kappes DJ. Basu J, et al. Among authors: grimes hl. Nat Immunol. 2023 Aug;24(8):1295-1307. doi: 10.1038/s41590-023-01549-3. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474652 Free PMC article.
An immunophenotype-coupled transcriptomic atlas of human hematopoietic progenitors.
Zhang X, Song B, Carlino MJ, Li G, Ferchen K, Chen M, Thompson EN, Kain BN, Schnell D, Thakkar K, Kouril M, Jin K, Hay SB, Sen S, Bernardicius D, Ma S, Bennett SN, Croteau J, Salvatori O, Lye MH, Gillen AE, Jordan CT, Singh H, Krause DS, Salomonis N, Grimes HL. Zhang X, et al. Among authors: grimes hl. Nat Immunol. 2024 Apr;25(4):703-715. doi: 10.1038/s41590-024-01782-4. Epub 2024 Mar 21. Nat Immunol. 2024. PMID: 38514887 Free PMC article.
Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease.
Gu Y, Harley IT, Henderson LB, Aronow BJ, Vietor I, Huber LA, Harley JB, Kilpatrick JR, Langefeld CD, Williams AH, Jegga AG, Chen J, Wills-Karp M, Arshad SH, Ewart SL, Thio CL, Flick LM, Filippi MD, Grimes HL, Drumm ML, Cutting GR, Knowles MR, Karp CL. Gu Y, et al. Among authors: grimes hl. Nature. 2009 Apr 23;458(7241):1039-42. doi: 10.1038/nature07811. Epub 2009 Feb 25. Nature. 2009. PMID: 19242412 Free PMC article.
134 results