Grimes G - Search Results

1

Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.

Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE. Lettice LA, et al. Among authors: grimes g. Dev Cell. 2012 Feb 14;22(2):459-67. doi: 10.1016/j.devcel.2011.12.010. Dev Cell. 2012. PMID: 22340503 Free PMC article.

2

Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development.

Reijns MA, Rabe B, Rigby RE, Mill P, Astell KR, Lettice LA, Boyle S, Leitch A, Keighren M, Kilanowski F, Devenney PS, Sexton D, Grimes G, Holt IJ, Hill RE, Taylor MS, Lawson KA, Dorin JR, Jackson AP. Reijns MA, et al. Among authors: grimes g. Cell. 2012 May 25;149(5):1008-22. doi: 10.1016/j.cell.2012.04.011. Epub 2012 May 10. Cell. 2012. PMID: 22579044 Free PMC article.

3

Anterior-posterior differences in HoxD chromatin topology in limb development.

Williamson I, Eskeland R, Lettice LA, Hill AE, Boyle S, Grimes GR, Hill RE, Bickmore WA. Williamson I, et al. Development. 2012 Sep;139(17):3157-67. doi: 10.1242/dev.081174. Development. 2012. PMID: 22872084 Free PMC article.

4

Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response.

Mackenzie KJ, Carroll P, Lettice L, Tarnauskaitė Ž, Reddy K, Dix F, Revuelta A, Abbondati E, Rigby RE, Rabe B, Kilanowski F, Grimes G, Fluteau A, Devenney PS, Hill RE, Reijns MA, Jackson AP. Mackenzie KJ, et al. Among authors: grimes g. EMBO J. 2016 Apr 15;35(8):831-44. doi: 10.15252/embj.201593339. Epub 2016 Feb 22. EMBO J. 2016. PMID: 26903602 Free PMC article.

5

Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors.

Peluso S, Douglas A, Hill A, De Angelis C, Moore BL, Grimes G, Petrovich G, Essafi A, Hill RE. Peluso S, et al. Among authors: grimes g. Elife. 2017 Sep 26;6:e28590. doi: 10.7554/eLife.28590. Elife. 2017. PMID: 28949289 Free PMC article.

6

Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation.

Benabdallah NS, Williamson I, Illingworth RS, Kane L, Boyle S, Sengupta D, Grimes GR, Therizols P, Bickmore WA. Benabdallah NS, et al. Mol Cell. 2019 Nov 7;76(3):473-484.e7. doi: 10.1016/j.molcel.2019.07.038. Epub 2019 Sep 4. Mol Cell. 2019. PMID: 31494034 Free PMC article.

7

DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency.

McLaughlin K, Flyamer IM, Thomson JP, Mjoseng HK, Shukla R, Williamson I, Grimes GR, Illingworth RS, Adams IR, Pennings S, Meehan RR, Bickmore WA. McLaughlin K, et al. Cell Rep. 2019 Nov 12;29(7):1974-1985.e6. doi: 10.1016/j.celrep.2019.10.031. Cell Rep. 2019. PMID: 31722211 Free PMC article.

8

Correction: Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops.

Williamson I, Boyle S, Grimes GR, Friman ET, Bickmore WA. Williamson I, et al. Among authors: grimes gr. Life Sci Alliance. 2023 Oct 23;7(1):e202302436. doi: 10.26508/lsa.202302436. Print 2024 Jan. Life Sci Alliance. 2023. PMID: 37871971 Free PMC article.

9

Ring1B compacts chromatin structure and represses gene expression independent of histone ubiquitination.

Eskeland R, Leeb M, Grimes GR, Kress C, Boyle S, Sproul D, Gilbert N, Fan Y, Skoultchi AI, Wutz A, Bickmore WA. Eskeland R, et al. Mol Cell. 2010 May 14;38(3):452-64. doi: 10.1016/j.molcel.2010.02.032. Mol Cell. 2010. PMID: 20471950 Free PMC article.

10

Histone H3 globular domain acetylation identifies a new class of enhancers.

Pradeepa MM, Grimes GR, Kumar Y, Olley G, Taylor GC, Schneider R, Bickmore WA. Pradeepa MM, et al. Among authors: grimes gr. Nat Genet. 2016 Jun;48(6):681-6. doi: 10.1038/ng.3550. Epub 2016 Apr 18. Nat Genet. 2016. PMID: 27089178 Free PMC article.

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