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An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals: A case study on paraquat.
Nunes C, Singh P, Mazidi Z, Murphy C, Bourguignon A, Wellens S, Chandrasekaran V, Ghosh S, Zana M, Pamies D, Thomas A, Verfaillie C, Culot M, Dinnyes A, Hardy B, Wilmes A, Jennings P, Grillari R, Grillari J, Zurich MG, Exner T. Nunes C, et al. Among authors: grillari r, grillari j. Toxicol In Vitro. 2022 Jun;81:105333. doi: 10.1016/j.tiv.2022.105333. Epub 2022 Feb 16. Toxicol In Vitro. 2022. PMID: 35182771 Free article.
Delineation of the key aspects in the regulation of epithelial monolayer formation.
Aschauer L, Gruber LN, Pfaller W, Limonciel A, Athersuch TJ, Cavill R, Khan A, Gstraunthaler G, Grillari J, Grillari R, Hewitt P, Leonard MO, Wilmes A, Jennings P. Aschauer L, et al. Among authors: grillari r, grillari j. Mol Cell Biol. 2013 Jul;33(13):2535-50. doi: 10.1128/MCB.01435-12. Epub 2013 Apr 22. Mol Cell Biol. 2013. PMID: 23608536 Free PMC article.
Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models.
Capinha L, Zhang Y, Holzer AK, Ückert AK, Zana M, Carta G, Murphy C, Baldovini J, Mazidi Z, Grillari J, Dinnyes A, van de Water B, Leist M, Commandeur JNM, Jennings P. Capinha L, et al. Among authors: grillari j. Arch Toxicol. 2023 Feb;97(2):523-545. doi: 10.1007/s00204-022-03436-6. Epub 2022 Dec 28. Arch Toxicol. 2023. PMID: 36576512 Free PMC article.
Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures.
Chandrasekaran V, Wellens S, Bourguignon A, Djidrovski I, Fransen L, Ghosh S, Mazidi Z, Murphy C, Nunes C, Singh P, Zana M, Armstrong L, Dinnyés A, Grillari J, Grillari-Voglauer R, Leonard MO, Verfaillie C, Wilmes A, Zurich MG, Exner T, Jennings P, Culot M. Chandrasekaran V, et al. Among authors: grillari j. Toxicol In Vitro. 2024 Apr 12;98:105826. doi: 10.1016/j.tiv.2024.105826. Online ahead of print. Toxicol In Vitro. 2024. PMID: 38615723 Free article.
hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.
Wieser M, Stadler G, Jennings P, Streubel B, Pfaller W, Ambros P, Riedl C, Katinger H, Grillari J, Grillari-Voglauer R. Wieser M, et al. Among authors: grillari voglauer r, grillari j. Am J Physiol Renal Physiol. 2008 Nov;295(5):F1365-75. doi: 10.1152/ajprenal.90405.2008. Epub 2008 Aug 20. Am J Physiol Renal Physiol. 2008. PMID: 18715936 Free article.
Generation of induced pluripotent stem cells from urine.
Zhou T, Benda C, Duzinger S, Huang Y, Li X, Li Y, Guo X, Cao G, Chen S, Hao L, Chan YC, Ng KM, Ho JC, Wieser M, Wu J, Redl H, Tse HF, Grillari J, Grillari-Voglauer R, Pei D, Esteban MA. Zhou T, et al. Among authors: grillari voglauer r, grillari j. J Am Soc Nephrol. 2011 Jul;22(7):1221-8. doi: 10.1681/ASN.2011010106. Epub 2011 Jun 2. J Am Soc Nephrol. 2011. PMID: 21636641 Free PMC article.
Generation of human induced pluripotent stem cells from urine samples.
Zhou T, Benda C, Dunzinger S, Huang Y, Ho JC, Yang J, Wang Y, Zhang Y, Zhuang Q, Li Y, Bao X, Tse HF, Grillari J, Grillari-Voglauer R, Pei D, Esteban MA. Zhou T, et al. Among authors: grillari voglauer r, grillari j. Nat Protoc. 2012 Dec;7(12):2080-9. doi: 10.1038/nprot.2012.115. Epub 2012 Nov 8. Nat Protoc. 2012. PMID: 23138349
A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers.
Khamina K, Diendorfer AB, Skalicky S, Weigl M, Pultar M, Krammer TL, Fournier CA, Schofield AL, Otto C, Smith AT, Buchtele N, Schoergenhofer C, Jilma B, Frank BJH, Hofstaetter JG, Grillari R, Grillari J, Ruprecht K, Goldring CE, Rehrauer H, Glaab WE, Hackl M. Khamina K, et al. Among authors: grillari r, grillari j. Int J Mol Sci. 2022 Jan 22;23(3):1226. doi: 10.3390/ijms23031226. Int J Mol Sci. 2022. PMID: 35163149 Free PMC article.
Independent human mesenchymal stromal cell-derived extracellular vesicle preparations differentially attenuate symptoms in an advanced murine graft-versus-host disease model.
Madel RJ, Börger V, Dittrich R, Bremer M, Tertel T, Phuong NNT, Baba HA, Kordelas L, Staubach S, Stein F, Haberkant P, Hackl M, Grillari R, Grillari J, Buer J, Horn PA, Westendorf AM, Brandau S, Kirschning CJ, Giebel B. Madel RJ, et al. Among authors: grillari r, grillari j. Cytotherapy. 2023 Aug;25(8):821-836. doi: 10.1016/j.jcyt.2023.03.008. Epub 2023 Apr 12. Cytotherapy. 2023. PMID: 37055321 Free article.
223 results