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The Pseudo-Natural Product Rhonin Targets RHOGDI.
Akbarzadeh M, Flegel J, Patil S, Shang E, Narayan R, Buchholzer M, Kazemein Jasemi NS, Grigalunas M, Krzyzanowski A, Abegg D, Shuster A, Potowski M, Karatas H, Karageorgis G, Mosaddeghzadeh N, Zischinsky ML, Merten C, Golz C, Brieger L, Strohmann C, Antonchick AP, Janning P, Adibekian A, Goody RS, Ahmadian MR, Ziegler S, Waldmann H. Akbarzadeh M, et al. Among authors: grigalunas m. Angew Chem Int Ed Engl. 2022 Apr 25;61(18):e202115193. doi: 10.1002/anie.202115193. Epub 2022 Mar 2. Angew Chem Int Ed Engl. 2022. PMID: 35170181 Free PMC article.
Dynamic Catalytic Highly Enantioselective 1,3-Dipolar Cycloadditions.
Yildirim O, Grigalunas M, Brieger L, Strohmann C, Antonchick AP, Waldmann H. Yildirim O, et al. Among authors: grigalunas m. Angew Chem Int Ed Engl. 2021 Sep 1;60(36):20012-20020. doi: 10.1002/anie.202108072. Epub 2021 Aug 3. Angew Chem Int Ed Engl. 2021. PMID: 34236754 Free PMC article.
Chemical Evolution of Natural Product Structure.
Grigalunas M, Brakmann S, Waldmann H. Grigalunas M, et al. J Am Chem Soc. 2022 Mar 2;144(8):3314-3329. doi: 10.1021/jacs.1c11270. Epub 2022 Feb 21. J Am Chem Soc. 2022. PMID: 35188375 Free PMC article.
Identification of Dihydroorotate Dehydrogenase Inhibitors Using the Cell Painting Assay.
Schölermann B, Bonowski J, Grigalunas M, Burhop A, Xie Y, Hoock JGF, Liu J, Dow M, Nelson A, Nowak C, Pahl A, Sievers S, Ziegler S. Schölermann B, et al. Among authors: grigalunas m. Chembiochem. 2022 Nov 18;23(22):e202200475. doi: 10.1002/cbic.202200475. Epub 2022 Oct 13. Chembiochem. 2022. PMID: 36134475 Free PMC article.
The Time and Place for Nature in Drug Discovery.
Young RJ, Flitsch SL, Grigalunas M, Leeson PD, Quinn RJ, Turner NJ, Waldmann H. Young RJ, et al. Among authors: grigalunas m. JACS Au. 2022 Oct 14;2(11):2400-2416. doi: 10.1021/jacsau.2c00415. eCollection 2022 Nov 28. JACS Au. 2022. PMID: 36465532 Free PMC article. Review.
A highly enantioselective intramolecular 1,3-dipolar cycloaddition yields novel pseudo-natural product inhibitors of the Hedgehog signalling pathway.
Liu J, Zhang R, Mallick S, Patil S, Wientjens C, Flegel J, Krupp A, Strohmann C, Grassin C, Merten C, Pahl A, Grigalunas M, Waldmann H. Liu J, et al. Among authors: grigalunas m. Chem Sci. 2023 Jun 21;14(29):7936-7943. doi: 10.1039/d3sc01240a. eCollection 2023 Jul 26. Chem Sci. 2023. PMID: 37502335 Free PMC article.
23 results