Griffith LG - Search Results

1

A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids.

Below CR, Kelly J, Brown A, Humphries JD, Hutton C, Xu J, Lee BY, Cintas C, Zhang X, Hernandez-Gordillo V, Stockdale L, Goldsworthy MA, Geraghty J, Foster L, O'Reilly DA, Schedding B, Askari J, Burns J, Hodson N, Smith DL, Lally C, Ashton G, Knight D, Mironov A, Banyard A, Eble JA, Morton JP, Humphries MJ, Griffith LG, Jørgensen C. Below CR, et al. Among authors: griffith lg. Nat Mater. 2022 Jan;21(1):110-119. doi: 10.1038/s41563-021-01085-1. Epub 2021 Sep 13. Nat Mater. 2022. PMID: 34518665 Free PMC article.

2

Capturing complex 3D tissue physiology in vitro.

Griffith LG, Swartz MA. Griffith LG, et al. Nat Rev Mol Cell Biol. 2006 Mar;7(3):211-24. doi: 10.1038/nrm1858. Nat Rev Mol Cell Biol. 2006. PMID: 16496023 Review.

3

Tethering of Epidermal Growth Factor (EGF) to Beta Tricalcium Phosphate (βTCP) via Fusion to a High Affinity, Multimeric βTCP-Binding Peptide: Effects on Human Multipotent Stromal Cells/Connective Tissue Progenitors.

Alvarez LM, Rivera JJ, Stockdale L, Saini S, Lee RT, Griffith LG. Alvarez LM, et al. Among authors: griffith lg. PLoS One. 2015 Jun 29;10(6):e0129600. doi: 10.1371/journal.pone.0129600. eCollection 2015. PLoS One. 2015. PMID: 26121597 Free PMC article.

4

A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties.

Clark AM, Wheeler SE, Young CL, Stockdale L, Shepard Neiman J, Zhao W, Stolz DB, Venkataramanan R, Lauffenburger D, Griffith L, Wells A. Clark AM, et al. Lab Chip. 2016 Dec 20;17(1):156-168. doi: 10.1039/c6lc01171c. Lab Chip. 2016. PMID: 27910972 Free PMC article.

5

Local remodeling of synthetic extracellular matrix microenvironments by co-cultured endometrial epithelial and stromal cells enables long-term dynamic physiological function.

Cook CD, Hill AS, Guo M, Stockdale L, Papps JP, Isaacson KB, Lauffenburger DA, Griffith LG. Cook CD, et al. Among authors: griffith lg. Integr Biol (Camb). 2017 Apr 18;9(4):271-289. doi: 10.1039/c6ib00245e. Integr Biol (Camb). 2017. PMID: 28317948 Free PMC article.

6

On-demand dissolution of modular, synthetic extracellular matrix reveals local epithelial-stromal communication networks.

Valdez J, Cook CD, Ahrens CC, Wang AJ, Brown A, Kumar M, Stockdale L, Rothenberg D, Renggli K, Gordon E, Lauffenburger D, White F, Griffith L. Valdez J, et al. Biomaterials. 2017 Jun;130:90-103. doi: 10.1016/j.biomaterials.2017.03.030. Epub 2017 Mar 23. Biomaterials. 2017. PMID: 28371736 Free PMC article.

7

OrgaQuant: Human Intestinal Organoid Localization and Quantification Using Deep Convolutional Neural Networks.

Kassis T, Hernandez-Gordillo V, Langer R, Griffith LG. Kassis T, et al. Among authors: griffith lg. Sci Rep. 2019 Aug 28;9(1):12479. doi: 10.1038/s41598-019-48874-y. Sci Rep. 2019. PMID: 31462669 Free PMC article.

8

Engineering PEG-based hydrogels to foster efficient endothelial network formation in free-swelling and confined microenvironments.

Brown A, He H, Trumper E, Valdez J, Hammond P, Griffith LG. Brown A, et al. Among authors: griffith lg. Biomaterials. 2020 Jun;243:119921. doi: 10.1016/j.biomaterials.2020.119921. Epub 2020 Mar 6. Biomaterials. 2020. PMID: 32172030 Free PMC article.

9

Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids.

Hernandez-Gordillo V, Kassis T, Lampejo A, Choi G, Gamboa ME, Gnecco JS, Brown A, Breault DT, Carrier R, Griffith LG. Hernandez-Gordillo V, et al. Among authors: griffith lg. Biomaterials. 2020 Sep;254:120125. doi: 10.1016/j.biomaterials.2020.120125. Epub 2020 May 25. Biomaterials. 2020. PMID: 32502894 Free PMC article.

10

A modular polymer microbead angiogenesis scaffold to characterize the effects of adhesion ligand density on angiogenic sprouting.

Sofman M, Brown A, Griffith LG, Hammond PT. Sofman M, et al. Among authors: griffith lg. Biomaterials. 2021 Jan;264:120231. doi: 10.1016/j.biomaterials.2020.120231. Epub 2020 Jul 16. Biomaterials. 2021. PMID: 33130485

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