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119 results

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Quantitative multiple fragment monitoring with enhanced in-source fragmentation/annotation mass spectrometry.
Bernardo-Bermejo S, Xue J, Hoang L, Billings E, Webb B, Honders MW, Venneker S, Heijs B, Castro-Puyana M, Marina ML, van den Akker EB, Griffioen M, Siuzdak G, Giera M, Sánchez-López E. Bernardo-Bermejo S, et al. Among authors: griffioen m. Nat Protoc. 2023 Apr;18(4):1296-1315. doi: 10.1038/s41596-023-00803-0. Epub 2023 Feb 8. Nat Protoc. 2023. PMID: 36755131 Free PMC article. Review.
Automated manufacture of ΔNPM1 TCR-engineered T cells for AML therapy.
Yonezawa Ogusuku IE, Herbel V, Lennartz S, Brandes C, Argiro E, Fabian C, Hauck C, Hoogstraten C, Veld S, Hageman L, Teppert K, Koutsoumpli G, Griffioen M, Mockel-Tenbrinck N, Schaser T, de Groot R, Johnston ICD, Lock D. Yonezawa Ogusuku IE, et al. Among authors: griffioen m. Mol Ther Methods Clin Dev. 2024 Feb 27;32(2):101224. doi: 10.1016/j.omtm.2024.101224. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38516690 Free PMC article.
Expanding the repertoire reveals recurrent, cryptic, and hematopoietic HLA class I minor histocompatibility antigens.
Fuchs KJ, van de Meent M, Honders MW, Khatri I, Kester MGD, Koster EAS, Koutsoumpli G, de Ru AH, van Bergen CAM, van Veelen PA, 't Hoen PAC, van Balen P, van den Akker EB, Veelken JH, Halkes CJM, Falkenburg JHF, Griffioen M. Fuchs KJ, et al. Among authors: griffioen m. Blood. 2024 May 2;143(18):1856-1872. doi: 10.1182/blood.2023022343. Blood. 2024. PMID: 38427583 Free article.
Mapping AML heterogeneity - multi-cohort transcriptomic analysis identifies novel clusters and divergent ex-vivo drug responses.
Severens JF, Karakaslar EO, van der Reijden BA, Sánchez-López E, van den Berg RR, Halkes CJM, van Balen P, Veelken H, Reinders MJT, Griffioen M, van den Akker EB. Severens JF, et al. Among authors: griffioen m. Leukemia. 2024 Apr;38(4):751-761. doi: 10.1038/s41375-024-02137-6. Epub 2024 Feb 15. Leukemia. 2024. PMID: 38360865
A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.
Giannakopoulou E, Lehander M, Virding Culleton S, Yang W, Li Y, Karpanen T, Yoshizato T, Rustad EH, Nielsen MM, Bollineni RC, Tran TT, Delic-Sarac M, Gjerdingen TJ, Douvlataniotis K, Laos M, Ali M, Hillen A, Mazzi S, Chin DWL, Mehta A, Holm JS, Bentzen AK, Bill M, Griffioen M, Gedde-Dahl T, Lehmann S, Jacobsen SEW, Woll PS, Olweus J. Giannakopoulou E, et al. Among authors: griffioen m. Nat Cancer. 2023 Oct;4(10):1474-1490. doi: 10.1038/s43018-023-00642-8. Epub 2023 Oct 2. Nat Cancer. 2023. PMID: 37783807 Free PMC article.
Human CD34+-derived complete plasmacytoid and conventional dendritic cell vaccine effectively induces antigen-specific CD8+ T cell and NK cell responses in vitro and in vivo.
van Eck van der Sluijs J, van Ens D, Brummelman J, Heister D, Sareen A, Truijen L, van Ingen Schenau DS, Heemskerk MHM, Griffioen M, Kester MGD, Schaap NPM, Jansen JH, van der Waart AB, Dolstra H, Hobo W. van Eck van der Sluijs J, et al. Among authors: griffioen m. Cell Mol Life Sci. 2023 Sep 20;80(10):298. doi: 10.1007/s00018-023-04923-4. Cell Mol Life Sci. 2023. PMID: 37728691 Free PMC article.
Acquisition of a glycosylated B-cell receptor drives follicular lymphoma toward a dark zone phenotype.
van Bergen CAM, Kloet SL, Quinten E, Sepúlveda Yáñez JH, Menafra R, Griffioen M, Jansen PM, Koning MT, Knijnenburg J, Navarrete MA, Kiełbasa SM, Veelken H. van Bergen CAM, et al. Among authors: griffioen m. Blood Adv. 2023 Oct 10;7(19):5812-5816. doi: 10.1182/bloodadvances.2023010725. Blood Adv. 2023. PMID: 37493974 Free PMC article. No abstract available.
Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain.
Meeuwsen MH, Wouters AK, Wachsmann TLA, Hagedoorn RS, Kester MGD, Remst DFG, van der Steen DM, de Ru AH, van Hees EP, Kremer M, Griffioen M, van Veelen PA, Falkenburg JHF, Heemskerk MHM. Meeuwsen MH, et al. Among authors: griffioen m. J Hematol Oncol. 2023 Feb 27;16(1):16. doi: 10.1186/s13045-023-01408-6. J Hematol Oncol. 2023. PMID: 36850001 Free PMC article.
119 results